| 主要論文・著書 |
- Miyata H, Imai H, Koseki H, Shimizu K, Abekura Y, Oka M, Kawamata T, Matsuda T, Nozaki K, Narumiya S, Aoki T#. Vasa vasorum formation is associated with rupture of intracranial aneurysms. J. Neurosurg. in press # corresponding author
- Koseki H, Miyata H, Shimo S, Ohno N, Mifune K, Shimano K, Yamamoto K, Nozaki K, Kasuya H, Narumiya S, Aoki T#. Two diverse hemodynamic forces, a mechanical stretch and a high wall shear stress, determine intracranial aneurysm formation. Transl. Stroke Res. in press # corresponding author
- Aoki T#, Koseki H, Miyata H, Itoh M, Kawaji H, Takizawa K, Kawashima A, Ujiie H, Higa T, Minamimura K, Kimura T, Kasuya H, Nozaki K, Morita A, Sano H, Narumiya S. RNA sequencing analysis revealed the induction of CCL3 expression in human intracranial aneurysms. Sci. Rep. 2019;9(1):10387. # corresponding author
- Aoki T, Saito M, Koseki H, Tsuji K, Tsuji A, Murata K, Kasuya H, Morita A, Narumiya S, Nozaki K; for MR macrophage imaging study investigators. Macrophage imaging of cerebral aneurysms with ferumoxytol: an exploratory study in an animal model and in patients. J. Stroke Cerebrovasc. Dis. 2017;26(10):2055-2064.
- Aoki T, Frosen J, Fukuda M, Bando K, Shioi G, Tsuji K, Ollikainen E, Nozaki K, Laakkonen J, Narumiya S. Prostaglandin E2-EP2-NF-B signaling in macrophages as a potential therapeutic target of intracranial aneurysm. Sci. Signal. 2017;10:eaah6037.
- Yoshimura Y, Murakami Y, Saitoh M, Yokoi T, Aoki T, Miura K, Ueshima H, Nozaki K; SSS Research Group Statin Use and Risk of Cerebral Aneurysm Rupture. A Hospital-Based Case-Control Study in Japan. J. Stroke Cerebrovasc. Dis. 2013;23(2):343-348.
- Aoki T, Nishimura M, Matsuoka T, Yamamoto K, Furuyashiki T, Kataoka H, Kitaoka S, Ishibashi R, Ishibazawa A, Miyamoto S, Morishita R, Ando J, Hashimoto N, Nozaki K, Narumiya S. PGE2-EP2 signaling in endothelium is activated to hemodynamic stress and induces cerebral aneurysm through an amplifying loop via NF-B. Br. J. Pharmacol. 2011;163(6):1237-1249.
- Aoki T, Kataoka H, Ishibashi R, Nozaki K, Hashimoto N. Impact of monocyte chemoattractant protein-1 deficiency on cerebral aneurysm formation. Stroke 2009;40(3):942-951.
- Aoki T, Kataoka H, Ishibashi R, Nozaki K, Hashimoto N. Simvastatin suppresses the progression of experimentally induced cerebral aneurysms in rats. Stroke 2008;39(4):1276-1285.
- Aoki T, Kataoka H, Shimamura M, Nakagami H, Wakayama K, Moriwaki T, Ishibashi R, Nozaki K, Morishita R, Hashimoto N. NF-B is a key mediator of cerebral aneurysm formation. Circulation 2007;116(24):2830-2840.
- Aoki T, Kataoka H, Morimoto M, Nozaki K, Hashimoto N. Macrophage-derived matrix metalloproteinase-2 and -9 promote the progression of cerebral aneurysms in rats. Stroke 2007;38(1):162-169.
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