| 主要論文・著書 | 論文
- Akiyama M, Nakayama D, Takeda S, Kokame K, Takagi J, Miyata T. Crystal structure and enzymatic activity of an ADAMTS-13 mutant with the East Asian-specific P475S polymorphism. J Thromb Haemost 11(7):1399-1406, 2013.
- Akiyama M, Takeda S, Kokame K, Takagi J, Miyata T. Crystal structures of the noncatalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor. ProcNatl Acad Sci U S A 106(46):19274-19279, 2009.
- Ono S, Matsui H, Noda M, Kasuda S, Yada N, Yoshimoto K, Akiyama M, Miyata T, Sugimoto M, Nishio K. Functional regulation of von Willebrand factor ameliorates acute ischemia-reperfusion kidney injury in mice. Sci Rep 9(1):14453, 2019.
- Urisono Y, Sakata A, Matsui H, Kasuda S, Ono S, Yoshimoto K, Nishio K, Sho M, Akiyama M, Miyata T, Okuchi K, Nishimura S, Sugimoto M. von Willebrand factor aggravates hepatic ischemia-reperfusion injury by promoting neutrophil recruitment in mice. Thromb Haemost 118(4):700-708, 2018.
- Maruyama K, Akiyama M, Miyata T, Kokame K. Protein S K196E mutation reduces its cofactor activity for APC but not for TFPI. Res Pract Thromb Haemost 2(4):751-756, 2018.
- Nagaya S, Akiyama M, Murakami M, Sekiya A, Asakura H, Morishita E. Congenital coagulation factor X deficiency: Genetic analysis of five patients and functional characterization of mutant factor X proteins. Haemophilia 24(5):774-785, 2018.
- Maruyama K, Akiyama M, Kokame K, Sekiya A, Morishita E, Miyata T. ELISA-based detection system for Protein S K196E mutation, a genetic risk factor for venous thromboembolism. PLoS One 10(7):e0133196, 2015.
総説
- 秋山正志. 血流による物理的力が招く血栓性疾患TTPと出血性疾患VWD 生化学 89(3): 343-350, 2017.
|
|---|
