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心臓再生制御部

スタッフ
安藤 康史

スタッフ紹介 [安藤 康史]

氏名 安藤 康史 NoPhoto
よみ あんどう　こうじ
所属・職務 心臓再生制御部・室長
内線番号
FAX番号
Eメール Ando.koji*ncvc.go.jp *が@
棟/部屋番号 研究所４F
専門 細胞生物学、血管生物学
主要論文・著書
  1. Ando K. (Co-corresponding author), Tong L., Peng D., Vázquez-Liébanas E., Chiyoda H., He L., Liu J., Kawakami K., Mochizuki N., Fukuhara S., Grutzendler J., Betsholtz C. KCNJ8/ABCC9-containing K-ATP channel modulates brain vascular smooth muscle development and neurovascular coupling. Dev. Cell. 2022. DOI: https://doi.org/10.1016/j.devcel.2022.04.019
  2. Peng D., Ando K (Co-corresponding author), Gloger M., Skoczylas R., Mochizuki N., Betsholtz C., Fukuhara S., Koltowska K. Proper migration of lymphatic endothelial cells requires survival and guidance cues from arterial mural cells. eLife. 2022; doi: https://doi.org/10.7554/eLife.74094
  3. Ando K (Corresponding author)., Ishii T., Fukuhara S. 'Zebrafish Vascular Mural Cell Biology: Recent Advances, Development, and Functions', Life, 2021; 11: 1041. Doi. doi.org/10.3390/life11101041
  4. Ando K (Co-corresponding author), Shih Y.H., Ebarasi L., Grosse A., Portman D., Chiba A., Mattonet K., Gerrif C., Stainier D.Y.R., Mochizuki N., Fukuhara S., Betsholtz C., Lawson N.D. Conserved and context-dependent roles for pdgfrb signaling during zebrafish vascular mural cell development. Dev. Biol. 2021. Nov. Vol(479), Pages 11-22. Doi: https://doi.org/10.1016/j.ydbio.2021.06.010
  5. Rho S. Oguri-Nakamura E., Ando K. Yamamoto K., Takagi Y., Fukuhara S. Protocol for analysis of integrin-mediated cell adhesion of lateral plate mesoderm cells isolated from zebrafish embryos. STAR Protocols. 2(2), 2021. doi:10.1016/j.xpro.2021.100428.
  6. Rho SS, Kobayashi I, Oguri-Nakamura E, Ando K, Fujiwara M, Kamimura N, Hirata H, Iida A, Iwai Y, Mochizuki N, Fukuhara S. Rap1b Promotes Notch-Signal-Mediated Hematopoietic Stem Cell Development by Enhancing Integrin-Mediated Cell Adhesion. Dev Cell. 2019 Jun 3;49(5):681-696.e6.
  7. Castro M, Laviña B, Ando K, Álvarez-Aznar A, Abu Taha A, Brakebusch C, Dejana E, Betsholtz C, Gaengel K. CDC42 Deletion Elicits Cerebral Vascular Malformations via Increased MEKK3-Dependent KLF4 Expression. Circ. Res. 2019 Apr 12;124(8):1240-1252.
  8. Rho SS, Kobayashi I, Oguri-Nakamura E, Ando K, Fujiwara M, Kamimura N, Hirata H, Iida A, Iwai Y, Mochizuki N, Fukuhara S. Rap1b Promotes Notch-Signal-Mediated Hematopoietic Stem Cell Development by Enhancing Integrin-Mediated Cell Adhesion. Dev Cell. 2019 Apr 9. pii: S1534-5807(19)30234-5.
  9. Ando K (Corresponding author), Wang W, Peng D, Chiba A, Lagendijk A, Barske L, Crup JG, Stainier DYR, Lendahl U, Koltowska K, Hogan BM, Fukuhara S, Mochizuki N, Betsholtz C. Periarterial specification of vascular mural cells from naïve mesenchyme requires Notch signaling. Development.  2019 Jan 25;146(2).
  10. Noishiki C, Yuge S, Ando K, Wakayama Y, Mochizuki N, Ogawa R, Fukuhara1 S. Live imaging of angiogenesis during cutaneous wound healing in adult zebrafish. Angiogenesis. 2019 May;22(2):341-354.
  11. He L, Vanlandewijck M, Mäe MA, Andrae J, Ando K, Del Gaudio F, Nahar K, Lebouvier T, Laviña B, Gouveia L, Sun Y, Raschperger E, Segerstolpe Å, Liu J, Gustafsson S, Räsänen M, Zarb Y, Mochizuki N, Keller A, Lendahl U, Betsholtz C. Single-cell RNA sequencing of mouse brain and lung vascular and vessel-associated cell types. Sci Data. 2018 Aug 21;5:180160.
  12. Vanlandewijck M, He L, Andaloussi Mäe M, Andrae J, Ando K, Del Gaudio F, Nahar K,   Lebouvier T, Laviña B, Leonor Gouveia L, Raschperger E, Räsänen M, Zarb Y, Mochizuki N,   Keller A, Lendahl U, Betsholtz C. A Molecular Atlas of Cell Types and Zonation in the Brain. Nature. 554:475–480. (2018)
  13. Takara K, Eino D, Ando K, Yasuda D, Naito H, Tsukada Y, Iba T, Wakabayashi T, Muramatsu F, Kidoya H, Fukuhara S, Mochizuki N, Ishii S, Kishima H, Takakura N. Lysophosphatidic Acid   Receptor 4 Activation Augments Drug Delivery in Tumors by Tightening Endothelial Cell-Cell  Contact. Cell Rep. 20(9):2072-208. (2017)
  14. Miura K, Nojiri T, Akitake Y, Ando K, Fukuhara S, Zenitani M, Kimura T, Hino J, Miyazato M, Hosoda H, Kangawa K. CCM2 and PAK4 act downstream of atrial natriuretic peptide signaling to promote cell spreading. Biochem J. 474(11):1897-1918. (2017)
  15. Nakajima H, Yamamoto K, Agarwala S, Terai K, Fukui H, Fukuhara S, Ando K, Miyazaki T,   Yokota Y, Schmelzer E, Belting HG, Affolter M, Lecaudey V, Mochizuki N. Flow-Dependent   Endothelial YAP Regulation Contributes to Vessel Maintenance. Dev. Cell. 40(6):523-536. (2017)
  16. Wild R, Klems A, Takamiya M, Hayashi Y, Strähle U, Ando K, Mochizuki N, van Impel A,   Schulte-Merker S, Krueger J, Preau L, le Noble F. Neuronal sFlt1 and Vegfaa determine venous   sprouting and spinal cord vascularization. Nat. Commun. 8: 13991 (2017)
  17. Ando K, Fukuhara S, Izumi N, Nakajima H, Fukui H, Kelsh RN, Mochizuki N. Clarification of mural cell coverage of vascular endothelial cells by live imaging of zebrafish. Development. 143(8):1328-39. (2016)
  18. He L, Vanlandewijck M, Raschperger E, Andaloussi Mäe M, Jung B, Lebouvier T, Ando K, Hofmann J, Keller A, Betsholtz C. Analysis of the brain mural cell transcriptome. Sci. Rep.  6:35108. (2016)
  19. Mikelis C, Simaan M, Ando K, Fukuhara S, Sakurai A, Amornphimoltham P, Masedunskas A, Weigert R, Chavakis T, Adams R, Offermanns S, Mochizuki N, Zheng Y, Gutkind JS. RhoA   and ROCK mediate histamine-induced vascular leakage and anaphylactic shock. Nat. Commun. 6: 6725. (2015)
  20. Kashiwada T, Fukuhara S, Terai K, Tanaka T, Wakayama Y, Ando K, Nakajima H, Fukui H, Yuge S, Saito. Y, Gemma A, Mochizuki N. β-Catenin-dependent transcription is central to   Bmp-mediated formation of venous vessels. Development. 142, 497-509. (2015)
  21. Wakayama Y, Fukuhara S, Ando K, Matsuda M, Mochizuki N. Cdc42 mediates Bmp-induced   sprouting angiogenesis through Fmnl3-driven assembly of endothelial filopodia in zebrafish. Dev. Cell. 32:109-122. (2015)
  22. Fukuhara S, Zhang J, Yuge S, Ando K, Wakayama Y, Sakaue-Sawano A, Miyawaki A,   Mochizuki N. Visualizing the cell-cycle progression of endothelial cells in zebrafish. Dev. Biol.  393: 10-23. (2014)
  23. Ando K, Fukuhara S, Moriya T, Obara Y, Nakahata N, Mochizuki N. Rap1potentiates  endothelial cell junctions by spatially controlling myosin II activity and actin organization. J. Cell Biol. 202: 901-916. (2013) (学位論文)
  24. Kwon HB, Fukuhara S, Asakawa K, Ando K, Kashiwada T, Kawakami K, Hibi M, Kwon YG,  Kim KW, Alitalo K, Mochizuki N. The parallel growth of motoneuron axons with the  dorsalaorta depends on Vegfc/Vegfr3 signaling in zebrafish. Development. 140:4081-4090.  (2013)
  25. Ando K, Obara Y, Sugama J, Kotani A, Koike N, Ohkubo S, Nakahata N. P2Y2 receptor   Gq/11 signaling at lipid rafts is required for UTP-induced cell migration in NG 108-15 cells. J. Pharmacol. Exp. Ther. 334:809-819. (2010)
  26. 安藤康史『血管新生における血管壁細胞動員機構とその役割』　医学のあゆみ270: (2019)
受賞
  • 第29回日本血管生物医学会 最優秀YIA(2021年)
  • 平成25年度 東北大学総長賞 (博士)
  • 平成22年度 東北大学国際高等教育研究機構　修士研究教育院生
  • Gordon Research Conferences (Angiogenesis), Poster Award (2015年)
  • The 18th International Vascular Biology Meeting Poster Award (2014年)　
  • 第21回日本血管生物医学会 優秀演題賞 (2013年)
学位 博士 (薬学) 東北大学
所属学会 血管生物医学会、日本分子生物学会
教育活動
その他の活動
研究者情報 https://researchmap.jp/koji-ando
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最終更新日：2022年05月31日

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