National Cerebral and Cardiovascular

Menu

  1. National Cerebral and Cardiovascular Center TOP
  2. Research Institute
  3. Departments
  4. Department of Cardiac Regeneration Biology
  5. Publications

Research Institute

Publications

  1. Tsuji M. Hematopoietic stem cells for perinatal brain injury. In: Shinataku H ed. Cell Therapy for Perinatal Brain Injury. Springer International Publishing, Japan [in press]
  2. Tsuji M, Shintaku H. Clinical trial of autologous cord blood cell therapy for neonatal hypoxic-ischemic encephalopathy (HIE). In: Shinataku H ed. Cell Therapy for Perinatal Brain Injury. Springer International Publishing, Japan [in press]
  3. Tsuji M, Enmi J, Moriguchi T, Yamazaki M, Zeniya T, Koshino K, Ohshima M, Iida H. Temporal profiles of cerebral blood flow after hypoxic-ischemic insult in immature rats: evaluation with 15O gas positron emission tomography. Int J Dev Neurosci [in press]
  4. Ohshima M, Coq JO, Otani K, Tsuji M. Establishment of a novel model of prenatal brain injury with intrauterine hypoperfusion in rats. Int J Dev Neurosci [in press]
  5. Ihara M. Autosomal dominant small vessel disease due to heterozygous HTRA1 mutations. Neurology, [in press]
  6. Iikuni S, Ono M, Watanabe H, Matsumura K, Yoshimura M, Kimura H, Ishibashi-Ueda H, Okamoto Y, Ihara M, Saji H. Imaging of Cerebral Amyloid Angiopathy with Bivalent 99mTc-Hydroxamamide Complexes. Sci Rep, [in press]
  7. Ono M, Doi Y, Watanabe H, Ihara M, Ozaki A, Saji H. Structure-Activity Relationships of Radioiodinated Diphenyl Derivatives with Different Conjugated Double Bonds as Ligands for α-Synuclein Aggregates. RSC Advances, [in press]
  8. Tojima M, Saito S, Yamamoto Y, Mizuno T, Ihara M, Fukuda H. CADASIL with a novel NOTCH3 Cys323Trp mutation presenting border zone infarcts: A case report and literature review. J Stroke Cerebrovasc Dis, [in press]
  9. Hattori Y, Maki T, Saito S, Yamamoto Y, Nagatsuka K, Ihara M. Influence of low-dose aspirin on cerebral amyloid angiopathy in mice. J Alzheimers Dis, [in press]
  10. Yasuno F, Kazui H, Morita N, Kajimoto K, Ihara M, Taguchi A, Yamamoto A, Matsuoka K, Kosaka J, Kudo T, Iida H, Kishimoto T, Nagatsuka K. High amyloid-β deposition related to depressive symptoms in older individuals with normal cognition: a pilot study. Int J Geriatr Psychiatry [in press]
  11. Kitamura A, Saito S, Maki A, Ayaki T, Oishi N, Kalaria RN, Hattori Y, Yamamoto Y, Urushitani M, Horsburgh K, Fukuyama H, Takahashi R, Ihara M. Gradual cerebral hypoperfusion in spontaneously hypertensive rats induces slowly evolving white matter abnormalities and impairs working memory. J Cereb Blood Flow Metab [in press]
  12. Ihara M, Yamamoto Y. Emerging evidence for pathogenesis of sporadic cerebral small vessel disease. Stroke 2016; 47: 554-560.
  13. Hattori Y, Enmi J, Iguchi S, Saito S, Yamamoto Y, Tsuji M, Nagatsuka K, Kalaria RN, Iida H, Ihara M. Gradual Carotid Artery Stenosis in Mice Closely Replicates Hypoperfusive Vascular Dementia in Humans. J Am Heart Assoc 2016; 5: e002757.
  14. Kalaria RN, Akinyemi R, Ihara M. Stroke Injury, cognitive Impairment and vascular dementia. Biochim Biophys Acta 2016; 1862: 915-925.
  15. Tonomura S, Ihara M, Kawano T, Tanaka T, Okuno Y, Saito S, Friedland RP, Kuriyama N, Nomura R, Watanabe Y, Nakano K, Toyoda K, Nagatsuka K. Intracerebral hemorrhage and deep microbleeds associated with cnm-positive Streptococcus mutans; a hospital cohort study. Sci Rep 2016; 6: 20074.
  16. Saito S, Ihara M. Interaction between cerebrovascular disease and Alzheimer pathology. Curr Opin Psychiatry 2016; 29:168-173.
  17. Manousopoulou A, Saito S, Yamamoto Y, Al-Daghri NM, Ihara M, Carare RO, Garbis SD. Hemisphere asymmetry of response to treatment in an Alzheimer's disease mouse model. J Alzheimers Dis 2016; 51: 333-338.
  18. Chen A, Akinyemi RO, Hase Y, Firbank MJ, Ndung'u MN, Foster V, Craggs LJL, Washida K, Okamoto Y, Thomas AJ, Polvikosk TM, Allan JM, Oakley AE, O'Brien JT, Horsburgh K, Ihara M, Kalaria RN. Frontal White Matter Hyperintensities, Clasmatodendrosis and Gliovascular Abnormalities in Ageing and Post-stroke Dementia. Brain 2016; 139: 242-258.
  19. Tokudome T, Kishimoto I, Shindo T, Kawakami H, Koyama T, Otani K, Nishimura H, Miyazato M, Kohno M, Nakao K, Kangawa K. Importance of endogenous atrial and brain natriuretic peptides in murine embryonic vascular and organ development. Endocrinology 2016;157:358-67.
  20. Tsuji M, Johnston MV. Cell-based therapies in neonatal stroke. p321-349. In: Hess DC ed. Cell Therapy for Brain Injury. Springer International Publishing, Switzerland (2015)
  21. Hattori T, Sato Y, Kondo T, Ichinohashi Y, Sugiyama Y, Yamamoto M, Kotani T, Hirata H, Hirakawa A, Suzuki S, Tsuji M, Ikeda T, Nakanishi K, Kojima S, Blomgren K, Hayakawa M. Administration of umbilical cord blood cells decreases hypoxic-ischemic brain injury in neonatal rats. Dev Neurosci 2015; 37: 95-104.
  22. Ohshima M, Taguchi A, Tsuda H, Sato Y, Yamahara K, Harada-Shiba M, Miyazato M, Ikeda T, Iida H, Tsuji M. Intraperitoneal and intravenous deliveries are not comparable in terms of drug efficacy and cell distribution in neonatal mice with hypoxia-ischemia. Brain Dev 2015; 37: 376-386.
  23. Kim J, Yoon H, Horie T, Burchett J, Restivo J, Rotllan N, Ramirez C, Verghese P, Ihara M, Hoe HS, Esau C, Fernandez-Hernando C, Holtzman D, Cirrito J, Ono K, Kim J. microRNA-33 Regulates ApoE Lipidation and Amyloid-β Metabolism in the Brain. J Neurosci 2015; 35:14717-14726.
  24. Miyamoto N, Maki T, Shindo A, Liang A, Maeda M, Egawa N, Itoh K, Lo E, Lok J, Ihara M, Arai K. Astrocytes promote oligodendrogenesis after white matter damage via brain-derived neurotrophic factor. J Neurosci 2015; 35: 14002-14008.
  25. Matsumura K, Ono M, Kitada A, Watanabe H, Yoshimura M, Iikuni S, Kimura H, Okamoto Y, Ihara M, Saji H. Structure-Activity Relationship Study of Heterocyclic Phenylethenyl and Pyridinylethenyl Derivatives as Tau-Imaging Agents That Selectively Detect Neurofibrillary Tangles in Alzheimer's Disease Brains. J Med Chem 2015; 58: 7241-57.
  26. Tanaka T, Yamagami H, Ihara M, Motoyama R, Fukuma K, Miyagi T, Nishimura K, Toyoda K, Nagatsuka K. Seizure outcomes and predictors of recurrent post-stroke seizure：a retrospective observational cohort study. PLoS ONE 2015; 10: e0136200.
  27. Taguchi A, Sakai C, Soma T, Kasahara Y, Stern DM, Kajimoto K, Ihara M, Daimon T, Yamahara K, Doi K, Kohara N, Nishimura H, Matsuyama T, Naritomi H, Sakai N, Nagatsuka K. Intravenous Autologous Bone Marrow Mononuclear Cell Transplantation for Stroke: Phase1/2a Clinical Trial in a Homogeneous Group of Stroke Patients. Stem Cells Dev 2015; 24: 2207-2218.
  28. Miyatani F, Kuriyama N, Watanabe I, Nakano K, Nomura R, Matsui D, Ozaki E, Koyama T, Nishigaki M, Yamamoto T, Mizuno T, Akazawa K, Takada A, Takeda K, Yamada K, Nakagawa M，Ihara M, Kanamura N，Friedland RP, Watanabe Y. Relationship between cariogenic bacteria (Cnm-positive Streptococcus mutans) and cerebral microbleeds in humans. Oral Dis 2015; 21: 886-893.
  29. Banik A, Brown RE, Bamburg J, Lahiri DK, Khurana D, Friedland RP, Chen W, Ding Y, Mudher A, Padjen AL, Mukaetova-Ladinska E, Ihara M, Srivastava E, Srivastava MVP, Masters CL, Kalaria RN, Anand A. Translation of pre-clinical studies into successful clinical trials for Alzheimer's disease: what are the roadblocks and how can they be overcome? J Alzheimer Dis 2015; 47: 815-843.
  30. Maesako M, Uemura M, Tashiro Y, Sasaki K, Watanabe K, Noda Y, Ueda K, Asada M, Kubota M, Okawa K, Ihara M, Shimohama S, Uemura K, Kinoshita A.　High fat diet enhances β-site cleavage of amyloid precursor protein (APP) via promoting β-site APP cleaving enzyme 1/Adaptor protein 2/clathrin complex formation. PLoS ONE 2015; 10: e0131199.
  31. Saito S, Yamamoto Y, Ihara M. Mild cognitive impairment: at the crossroad of neurodegeneration and vascular dysfunction. Curr Alzheimer Res 2015; 12: 507-512.
  32. Yasuno F, Kazui H, Morita N, Kajimoto K, Ihara M, Taguchi A, Yamamoto A, Matsuoka K, Kosaka J, Kudo T, Iida H, Kishimoto T, Nagatsuka K. Low amyloid-β deposition correlates with high education in cognitively normal older adults: A pilot study. Int J Geriatr Psychiatry 2015; 30: 919-926.
  33. Maki T, Maeda M, Uemura M, Lo EK, Terasaki Y, Liang AC, Shindo A, Choi YK, Taguchi A, Matsuyama T, Takahashi R, Ihara M, Arai K. Potential interactions between pericytes and oligodendrocyte precursor cells in perivascular regions of cerebral white matter. Neurosci Lett 2015; 597: 164-169.
  34. Yasuno F, Kazui H, Yamamoto A, Morita N, Kajimoto K, Ihara M, Taguchi A, Matsuoka K, Kosaka J, Tanaka T, Kudo T, Takeda M, Nagatsuka, Iida H, Kishimoto T. Resting-state synchrony between the retrosplenial cortex and anterior medial cortical structures relates to memory complaints in subjective cognitive impairment. Neurobiol Aging 2015; 36:2145-2152.
  35. Holland PR, Searcy JL, Salvadores N, Scullion G, Chen G, Lawson G, Scott F, Bastin ME, Ihara M, Kalaria RN, Wood ER, Smith C, Wardlaw JM, Horsburgh K. Gliovascular disruption and cognitive deficits in a mouse model with features of small vessel disease. J Cereb Blood Flow Metab 2015; 35:1005-1014.
  36. Maki T, Takahashi Y, Miyamoto N, Liang AC, Osumi N, Ihara M, Lo EH, Arai K. Adrenomedullin promotes differentiation of oligodendrocyte precursor cells into myelin-basic-protein expressing oligodendrocytes under pathological conditions in vitro. Stem Cell Res 2015; 15: 68-74.
  37. Fukuma K, Ihara M, Tanaka T, Morita Y, Toyoda K, Nagatsuka K. Intracranial cerebral artery dissection of anterior circulation as a cause of convexity subarachnoid hemorrhage. Cerebrovasc Dis 2015; 40: 45-51.
  38. Craggs LJL, Fenwick R, Oakley AE, Ihara M, Kalaria RN. Immunolocalisation of PDGFRβ and pericytes in CADASIL. Neuropath Appl Neurobiol 2015; 41: 557-570.
  39. Hattori Y, Enmi JI, Kitamura A, Yamamoto Y, Saito S, Takahashi Y, Iguchi S, Tsuji M, Yamahara K, Nagatsuka K, Iida H, Ihara M. A novel mouse model of subcortical infarcts with dementia. J Neurosci 2015; 35: 3915-3928.
  40. Hattori Y, Okamoto Y, Nagatsuka K, Takahashi R, Kalaria RN, Kinoshita M, Ihara M. SIRT1 attenuates severe ischemic damage by preserving cerebral blood flow. NeuroReport 2015; 26: 113-117.
  41. Watanabe H, Ono M, Iikuni S, Kimura H, Okamoto Y, Ihara M, Saji H. Synthesis and biological evaluation of 123I-Labeled pyridyl benzoxazole derivatives: novel β-amyloid imaging probes for single-photon emission computed tomography. RSC Advances 2015; 5: 1009-1015.
  42. Yoshihara F, Tokudome T, Kishimoto I, Otani K, Kuwabara A, Horio T, Kawano Y, Kangawa K. Aggravated renal tubular damage and interstitial fibrosis in mice lacking guanylyl cyclase-A (GC-A), a receptor for atrial and B-type natriuretic peptides. Clin Exp Nephrol 2015;19:197-207.
  43. Nojiri T, Hosoda H, Tokudome T, Miura K, Ishikane S, Otani K, Kishimoto I, Shintani Y, Inoue M, Kimura T, Sawabata N, Minami M, Nakagiri T, Funaki S, Takeuchi Y, Maeda H, Kidoya H, Kiyonari H, Shioi G, Arai Y, Hasegawa T, Takakura N, Hori M, Ohno Y, Miyazato M, Mochizuki N, Okumura M, Kangawa K. Atrial natriuretic peptide prevents cancer metastasis through vascular endothelial cells. Proc Natl Acad Sci U S A 2015;112:4086-91.
  44. Mao Y, Tokudome T, Kishimoto I, Otani K, Nishimura H, Yamaguchi O, Otsu K, Miyazato M, Kangawa K. Endogenous ghrelin attenuates pressure overload-induced cardiac hypertrophy via a cholinergic anti-inflammatory pathway. Hypertension 2015;65:1238-44.
  45. Tsuji M, Taguchi A, Ohshima M, Kasahara Y, Sato Y, Tsuda H, Otani K, Yamahara K, Ihara M, Harada-Shiba M, Ikeda T, Matsuyama T. Effects of intravenous administration of umbilical cord blood CD34+ cells in a mouse model of neonatal stroke. Neuroscience 2014; 263: 148-158.
  46. Ayaki T, Ito H, Fukushima H, Inoue T, Kondo T, Ikemoto A, Asano T, Shodai A, Fukui S, Nakano S, Kusaka H, Yamashita H, Ihara M, Matsumoto R, Kawamata J, Urushitani M, Kawakami H, Takahashi R. Immunoreactivity of valosin-containing protein in sporadic amyotrophic lateral sclerosis and in a case of its novel mutant. Acta Neuropathol Commun 2014; 2: 172.
  47. Saito S and Ihara M. New therapeutic approaches for Alzheimer's disease and cerebral amyloid angiopathy. Front Aging Neurosci 2014; 6: 290.
  48. Washida K, Ihara M, Tachibana H, Sekiguchi K, Kowa H, Kanda F, Toda T. Association of the ASCO Classification with the Executive Function Subscores of the Montreal Cognitive Assessment in Patients with Postischemic Stroke. J Stroke Cerebrovasc Dis 2014; 23: 2250-2255.
  49. Igarashi K, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Yamauchi A, Toriyama Y, Tanaka M, Liu T, Xian X, Imai A, Zhai L, Owa S, Koyama T, Uetake R, Ihara M, Shindo T. Pathophysiological roles of adrenomedullin-RAMP2 system in acute and chronic cerebral ischemia. Peptides 2014; 62: 21-31.
  50. Hattori Y, Okamoto Y, Maki T, Yamamoto Y, Oishi N, Yamahara K, Nagatsuka K, Takahashi R, Kalaria RN, Fukuyama H, Kinoshita M, Ihara M. Silent information regulator 2 homolog 1 counters cerebral hypoperfusion injury by deacetylating endothelial nitric oxide synthase. Stroke 2014; 45: 3403-3411.
  51. Hattori Y, Kitamura A, Tsuji M, Nagatsuka K, Ihara M. Motor and cognitive impairment in a mouse model of ischemic carotid artery disease. Neurosci Lett 2014; 581: 1-6.
  52. Maki T, Okamoto Y, Carare R, Hase Y, Hattori Y, Hawkes C, Saito S, Yamamoto Y, Terasaki Y, Ishibashi-Ueda, H, Taguchi A, Takahashi R, Miyakawa T, Kalaria R, Lo EH, Arai K, Ihara M. Phosphodiesterase Ⅲ inhibitor promotes drainage of cerebrovascular β-amyloid. Ann Clin Transl Neurol 2014; 1: 519-533.
  53. Nanri K, Mitoma H, Ihara M, Tanaka N, Taguchi T, Takeguchi M, Ishiko T, Mizusawa H. Gluten ataxia in Japan. Cerebellum 2014; 13: 623-627.
  54. Nakaoku Y, Ihara M, Hase Y, Okamoto Y, Saito S, Hishizawa M, Uemura K, Kuwahara M, Oka N, Kusunoki S, Takahashi R. Possible paraneoplastic etiology in a case of Guillain-Barre syndrome with tumoral expression of ganglioside GM3. Neurol Clin Neurosci 2014; 2: 169-171.
  55. Ihara M, Kalaria RN. Understanding and preventing the development of post-stroke dementia. Expert Rev Neurother 2014; 14: 1067-1077.
  56. Seo JH, Maki T, Maeda M, Miyamoto N, Liang A, Hayakawa K, Pham LD, Suwa F, Taguchi A, Matsuyama T, Ihara M, Kim KW, Lo EH, Arai K. Oligodendrocyte precursor cells support blood-brain barrier integrity via TGF-β signaling. PLoS ONE 2014; 9: e103174.
  57. Hattori Y, Kitamura A, Nagatsuka K, Ihara M. A novel mouse model of ischemic carotid artery disease. PLoS ONE 2014; 9: e100257.
  58. Craggs LJ, Yamamoto Y, Ihara M, Fenwick R, Slade JY, Oakley A, Roeber S, Duering M, Kretzschmar H, Kalaria RN. White matter pathology and disconnection in the frontal lobe in CADASIL. Neuropath Appl Neurobiol 2014; 40: 591-602.
  59. Craggs LJ, Yamamoto Y, Ihara M, Fenwick R, Burke M, Oakley AE, et al. White matter pathology and disconnection in the frontal lobe in CADASIL. Neuropathol Appl Neurobiol 2014; 40: 591-602.
  60. Ihara M, Nishino M, Taguchi A, Yamamoto Y, Hattori Y, Saito S, Takahashi Y, Tsuji M, Kasahara Y, Takata Y, Okada M. Cilostazol add-on therapy in patients with mild dementia receiving donepezil: a retrospective study. PLoS ONE 2014; 9: e89516.
  61. Tsuji M, Taguchi A, Ohshima M, Kasahara Y, Sato Y, Tsuda H, Otani K, Yamahara K, Ihara M, Harada-Shiba M, Ikeda T, Matsuyama T. Effects of intravenous administration of umbilical cord blood CD34+ cells in a mouse model of neonatal stroke. Neuroscience 2014; 263: 148-158.
  62. Ihara M, Taguchi A, Maki T, Washida K, Tomimoto H. A mouse model of chronic cerebral hypoperfusion characterizing features of cognitive impairment. Methods Mol Biol 2014; 1135: 95-102.
  63. Tsuda H, Yamahara K, Otani K, Okumi M, Yazawa K, Kaimori J, Taguchi A, Kangawa K, Ikeda T, Takahara S, Isaka Y. Transplantation of allogenic fetal membrane-derived mesenchymal stem cells protect against ischemia-reperfusion- induced acute kidney injury. Cell Transplant 2014;23:889-99.
  64. Yamahara K, Harada K, Ohshima M, Ishikane S, Ohnishi S, Tsuda H, Otani K, Taguchi A, Soma T, Ogawa H, Katsuragi S, Yoshimatsu J, Harada-Shiba M, Kangawa K, Ikeda T. Comparison of angiogenic, cytoprotective, and immunosuppressive properties of human amnion- and chorion-derived mesenchymal stem cells. PLos One 2014;9:e88319.
  65. Mao Y, Tokudome T, Kishimoto I, Otani K, Miyazato M, Kangawa K. One dose of oral hexarelin protects chronic cardiac function after myocardial infarction. Peptide 2014;56:156-62.
  66. Popov S, Takemori H, Tokudome T, Mao Y, Otani K, Mochizuki N, Pires N, Pinho MJ, Franco-Cereceda A, Torielli L, Ferrandi M, Hamsten A, Soares-da-Silva P, Eriksson P, Bertorello AM, Brion L. Lack of salt-inducible kinase 2 (SIK2) prevents the development of cardiac hypertrophy in response to chronic high-salt intake. PLos One 2014;9:e95771.
  67. Tsuji M, Ohshima M, Taguchi A, Kasahara Y, Ikeda T, Matsuyama T. A novel reproducible model of neonatal stroke in mice: comparison with a hypoxia-ischemia model. Exp Neurol 2013; 247: 218-225.
  68. Kalaria RN, Ihara M. Vascular and neurodegenerative pathways--will they meet? Nat Rev Neurol 2013; 9: 487-488.
  69. Ono M, Cheng Y, Kimura H, Watanabe H, Matsumura K, Yoshimura M, Iikuni S, Okamoto Y, Ihara M, Takahashi R, Saji H. Development of Novel 123I-Labeled Pyridyl Benzofuran Derivatives for SPECT Imaging of β-Amyloid Plaques in Alzheimer's Disease. PLoS ONE 2013; 8: e74104.
  70. Yoshimura M, Ono M, Matsumura K, Watanabe H, Kimura H, Cui M, Nakamoto Y, Togashi K, Okamoto Y, Ihara M, Takahashi R, Saji H. Structure-activity Relationships and in vivo Evaluation of Quinoxaline Derivatives for PET Imaging of β-Amyloid Plaques. ACS Med Chem Lett 2013; 4: 596-600.
  71. Taguchi A, Takata Y, Ihara M, Kasahara Y, Tsuji M, Nishino M, Stern D, Okada M. Cilostazol improves cognitive function in patients with mild cognitive impairment: A retrospective analysis. Psychogeriatrics 2013; 13: 164-169.
  72. Kasahara Y, Ihara M, Taguchi A. Experimental and clinical challenge for neuroregeneration following stroke. Front Neurol Neurosci 2013; 32: 69-75.
  73. Kasahara Y, Ihara M, Nakagomi T, Momota Y, Stern DM, Matsuyama T, Taguchi A. A highly reproducible model of cerebral ischemia/reperfusion with extended survival in CB-17 mice. Neurosci Res 2013; 76: 163-168.
  74. Ihara M, Okamoto Y, Hase Y, Takahashi R. Association of Physical Activity with the Visuospatial/Executive Functions of the Montreal Cognitive Assessment in Patients with Vascular Cognitive Impairment. J Stroke Cerebrovasc Dis 2013; 22: e146-151.
  75. Akinyemi R, Mukaetova-Ladinska E, Attems J, Ihara M, Kalaria RN. Vascular risk factors and neurodegeneration in ageing related dementias: Alzheimer's disease and vascular dementia. Curr Alzheimer Res 2013; 10: 642-53.
  76. Yamamoto Y, Craggs LJL, Watanabe A, Booth T, Attems J, Low RWC, et al. Brain Microvascular Accumulation and Distribution of the NOTCH3 Ectodomain and Granular Osmiophilic Material in CADASIL. J Neuropathol Exp Neurol. 2013; 72: 416-431.
  77. Matsumura K, Ono M, Yoshimura M, Kimura H, Watanabe H, Okamoto Y, Ihara M, Takahashi R, Saji H. Synthesis and Biological Evaluation of Novel Styryl Benzimidazole Derivatives as Probes for Imaging of Neurofibrillary Tangles in Alzheimer's Disease. Bioorg Med Chem 2013; 21: 3356-3362.
  78. Otani K, Zeniya T, Kawashima H, Fukuda H, Hashikawa Y, Moriguchi T, Inubushi M, Iida H, Yamahara K. Noninvasive Spatial and Temporal Tracking of Multilayered Cell Sheet on Infarcted Heart Using Reporter Gene Imaging. Circulation, 2013, 128.22 Supplement: A13480.
  79. Otani K, Yamahara K. Feasibility of lactadherin-bearing clinically available microbubbles as ultrasound contrast agent for angiogenesis. Mol Imaging Biol 2013; 15: 534-541.
  80. Mao Y, Tokudome T, Otani K, Kishimoto I, Miyazato M, Kangawa K. Excessive sympathoactivation and deteriorated heart function after myocardial infarction in male ghrelin knockout mice. Endocrinology 2013;154:1854-63.
  81. Otani K, Yamahara K. Feasibility of lactadherin-bearing clinically available microbubbles as ultrasound contrast agent for angiogenesis. Mol Imaging Biol 2013;15:534-41.
  82. Mao Y, Tokudome T, Kishimoto I, Otani K, Hosoda H, Nagai C, Minamino N, Miyazato M, Kangawa K. Hexarelin treatment in male ghrelin knockout mice after myocardial infarction. Endocrinology 2013;154:3847-54.

last updated：2022/06/27

Site setting