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Pathophysiological studies on life-style related diseases

Related several publications

  1. Iwai N, Yasui N, Naraba H, et al. Klk1 as one of the genes contributing to hypertension in Dahl salt sensitive rat. Hypertension. 2005; 45: 947-953. (Web of Science Citation=16)
  2. Yamawaki H, Iwai N. Mechanisms underlying nano-sized air-pollution mediated progression of atherosclerosis:carbon black causes cytotoxic injury/inflammation and inhibits cell growth in vascular endothelial cells. Circ J. 2006; 70:129-140. (61)
  3. Yamawaki H, Iwai N. Cytotoxicity of water soluble fullerene in vascular endothelial cells. Am J Physiol Cell Physiol. 2006; 290: C1495-C1502. (83)
  4. Niwa Y, Hiura Y, Murayama T, et al. Nano-sized carbon black exposure exacerbates atherosclerosis in LDL-receptor knockout mice. Circ J. 2007; 71: 1157-1161. (22)
  5. Niwa Y, Hiura Y, Sawamura H, Iwai N. Inhalation exposure to carbon black induces inflammatory response in rats. Circ J. 2008;72:144-149. (21)
  6. Ji X, Naito Y, Hirokawa G, et al. P2rx7 receptor antagonism attenuates the hypertension and renal injury in Dahl salt-sensitive rats. Hypertens Res 2012; 35:173-9 (5)
  7. Ji X, Naito Y, Weng H, et al. P2rx7 deficiency attenuates hypertension and renal injury in deoxycorticosterone acetate (DOCA)-salt hypertension. Am J Physiol Renal Physiol. 2012; 303:1207-15 (7)
  8. Weng H, Ji X, Naito Y, et al. Pex11α deficiency impairs peroxisome elongation and division and contributes to nonalcoholic fatty liver in mice. Am J Physiol Endocrinol Metab 2013; 304:E187-96 (3)
  9. Ji X, Naito Y, Weng H, et al. Renoprotective mechsnisms of pirfenidone in hypertension-induced renal injury: through anti-fibrotic and anti-oxidative pathways. Biomed Res 2013;34:309-319
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