冠疾患科・血管科
研究活動の概要

当科はCCUおよび冠疾患科、血管科からなり、研究内容として虚血性心疾患、循環器救急医療、動脈硬化、大血管・末梢血管を対象とした臨床研究ならびに臨床応用を目指した基礎研究を実施しています。

具体的には、以下のテーマで研究を行っています。

  1. 心臓MRIを用いた不安定プラークの検出と治療効果判定に関する研究
  2. 心臓MRIを用いた低心機能患者の左室内血栓と脳梗塞、抗凝固治療との相関に関する研究
  3. 冠動脈内イメージングモダリティと心臓MRIを用いた冠動脈プラーク・イメージング
  4. 急性非代償性心不全（ADHF）に関する研究
  5. 腎動脈狭窄症に対する血管内治療（EVT）に関する研究（CARMEL）
  6. 血液中PCSK9と冠動脈硬化症の関係解明研究
  7. 家族性高コレステロール血症を有する冠動脈疾患症例の特徴、長期予後調査

2019年の主な研究成果
  • 院外心停止患者に対する市民によるAED（自動体外式除細動器）を用いた除細動実施が、その時点で自己心拍再開へと至らなかったとしても、その後の神経学的転帰を改善させる可能性を世界で初めて明らかにした。LANCET誌に発表した。
  • 冠動脈内イメージングモダリィテイと心臓MRIを用いた冠動脈プラーク・イメージングをEuropean Heart Journal Cardiovascular Imagingに発表した。
  • たこつぼ型心筋症における心臓MRI検査T1-mappingの有用性をEuropean Heart Journal誌に発表した。
  • 原因不明脳梗塞患者に対して心臓MRI使用によって左室内血栓を同定する研究をStroke誌に発表した。
  • 初回心筋梗塞患者で左室内血栓を合併する頻度と抗血小板療法と抗凝固療法の影響に関する検討をEuropean Heart Journal誌に発表した。
研究業績
  1. Kataoka Y, Hosoda K, Makino H, Matsubara M, Matsuo M, Ohata Y, Koezuka R, Tamanaha T, Tomita T, Honda-Kohmo K, Noguchi M, Son C, Nishimura K, Asaumi Y, Miyamoto Y, Noguchi T, Yasuda S. The efficacy of glycemic control with continuous glucose monitoring on atheroma progression: rationale and design of the Observation of Coronary Atheroma Progression under Continuous Glucose Monitoring Guidance in Patients with Type 2 Diabetes Mellitus (OPTIMAL). Cardiovascular Diagnosis and Therapy. 9, 431-438, 2019.
  2. Honda S, Nishihira K, Kojima S, Takegami M, Asaumi Y, Suzuki M, Kosuge M, Takahashi J, Sakata Y, Takayama M, Sumiyoshi T, Ogawa H, Kimura K, Yasuda S; JAMIR investigators. Rationale, Design, and Baseline Characteristics of the Prospective Japan Acute Myocardial Infarction Registry (JAMIR). Cardiovascular Drugs and Therapy. 33, 97-103, 2019.
  3. Marume K, Takashio S, Nakanishi M, Kumasaka L, Fukui S, Nakao K, Arakawa T, Yanase M, Noguchi T, Yasuda S, Goto Y. Efficacy of Cardiac Rehabilitation in Heart Failure Patients With Low Body Mass Index. Circulation Journal. 83, 334-341, 2019.
  4. Nakanishi M, Miura H, Nakao K, Fujino M, Arakawa T, Fukui S, Hasegawa T, Yanase M, Noguchi T, Goto Y, Yasuda S. Combination of Peak Exercise Systolic Blood Pressure and Left Atrial Diameter as a Novel Non-Spirometry Prognostic Predictor Comparable to Peak Oxygen Uptake for Heart Failure With Reduced Ejection Fraction. Circulation Journal. 83, 1528-1537, 2019.
  5. Yagyu T, Yasuda S, Nagaya N, Doi K, Nakatani T, Satomi K, Shimizu W, Kusano K, Anzai T, Noguchi T, Ohgushi H, Kitamura S, Kangawa K, Ogawa H. Long-Term Results of Intracardiac Mesenchymal Stem Cell Transplantation in Patients With Cardiomyopathy. Circulation Journal. 83, 1590-1599, 2019.
  6. Kanaya T, Noguchi T, Otsuka F, Asaumi Y, Kataoka Y, Morita Y, Miura H, Nakao K, Fujino M, Kawasaki T, Nishimura K, Inoue T, Narula J, Yasuda S. Optical coherence tomography-verified morphological correlates of high-intensity coronary plaques on non-contrast T1-weighted magnetic resonance imaging in patients with stable coronary artery disease. European Heart Journal-Cardiovascular Imaging. 20, 75-83, 2019.
  7. Aikawa Y, Noguchi T, Morita Y, Tateishi E, Kono A, Miura H, Komori Y, Asaumi Y, Fukuda T, Yasuda S. Clinical impact of native T1 mapping for detecting myocardial impairment in takotsubo cardiomyopathy. European Heart Journal-Cardiovascular Imaging. 20, 1147-1155, 2019.
  8. Nakao K, Yasuda S, Nishimura K, Noguchi T, Nakai M, Miyamoto Y, Sumita Y, Shishido T, Anzai T, Ito H, Tsutsui H, Saito Y, Komuro I, Ogawa H. Prescription Rates of Guideline-Directed Medications Are Associated With In-Hospital Mortality Among Japanese Patients With Acute Myocardial Infarction: A Report From JROAD-DPC Study. Journal of the American Heart Association. 8, e009692, 2019.
  9. Chinen D, Nagai T, Uemura K, Aikawa Y, Motokawa T, Asaumi Y, Ogo T, Kanzaki H, Noguchi T, Anzai T, Shimizu W, Ogawa H, Sugimachi M, Yasuda S. Clinical Usefulness of an Echo-Doppler Model in Predicting Elevated Pulmonary Capillary Wedge Pressure in Patients With Heart Failure. American Journal of Cardiology. 123, 1464-1469, 2019.
  10. Kataoka N, Nagase S, Kamakura T, Nakajima K, Wada M, Yamagata K, Ishibashi K, Inoue YY, Miyamoto K, Noda T, Aiba T, Izumi C, Noguchi T, Yasuda S, Kamakura S, Kusano K. Clinical Differences in Japanese Patients Between Brugada Syndrome and Arrhythmogenic Right Ventricular Cardiomyopathy With Long-Term Follow-Up. American Journal of Cardiology. 124, 715-722, 2019.
  11. Kashiwa A, Koyama F, Miyamoto K, Kamakura T, Wada M, Yamagata K, Ishibashi K, Inoue Y, Okamura H, Nagase S, Noda T, Aiba T, Watanabe S, Goto A, Yasuda S, Kusano K. Performance of an atrial fibrillation detection algorithm using continuous pulse wave monitoring. Annals of Noninvasive Electrocardiology. 24, e12615, 2019.
  12. Kuroiwa Y, Uchida A, Yamashita A, Miyati T, Maekawa K, Gi T, Noguchi T, Yasuda S, Imamura T, Asada Y. Coronary high-signal-intensity plaques on T-1-weighted magnetic resonance imaging reflect intraplaque hemorrhage. Cardiovascular Pathology. 40, 24-31, 2019.
  13. Nagayama T, Nagase S, Kamakura T, Wada M, Ishibashi K, Inoue YY, Miyamoto K, Noda T, Aiba T, Takaki H, Sugimachi M, Shimizu W, Noguchi T, Yasuda S, Kamakura S, Kusano K. Clinical and Electrocardiographic Differences in Brugada Syndrome With Spontaneous or Drug-Induced Type 1 Electrocardiogram. Circulation Journal. 83, 532-539, 2019.
  14. Nakano H, Omote K, Nagai T, Nakai M, Nishimura K, Honda Y, Honda S, Iwakami N, Sugano Y, Asaumi Y, Aiba T, Noguchi T, Kusano K, Yokoyama H, Yasuda S, Ogawa H, Chikamori T, Anzai T; NaDEF Investigators. Comparison of Mortality Prediction Models on Long-Term Mortality in Hospitalized Patients With Acute Heart Failure - The Importance of Accounting for Nutritional Status -. Circulation Journal. 83, 614-621, 2019.
  15. Kanaoka K, Okayama S, Nakai M, Sumita Y, Nishimura K, Kawakami R, Okura H, Miyamoto Y, Yasuda S, Tsutsui H, Komuro I, Ogawa H, Saito Y. Hospitalization Costs for Patients With Acute Congestive Heart Failure in Japan. Circulation Journal. 83, 1025-1031, 2019.
  16. Okuno T, Aoki J, Tanabe K, Nakao K, Ozaki Y, Kimura K, Ako J, Noguchi T, Yasuda S, Suwa S, Fujimoto K, Nakama Y, Morita T, Shimizu W, Saito Y, Hirohata A, Morita Y, Inoue T, Okamura A, Mano T, Hirata K, Shibata Y, Owa M, Tsujita K, Funayama H, Kokubu N, Kozuma K, Uemura S, Tobaru T, Saku K, Ohshima S, Nishimura K, Miyamoto Y, Ogawa H, Ishihara M. Admission Heart Rate Is a Determinant of Effectiveness of Beta-Blockers in Acute Myocardial Infarction Patients. Circulation Journal. 83, 1054-1063, 2019.
  17. Uemura S, Okamoto H, Nakai M, Nishimura K, Miyamoto Y, Yasuda S, Tanaka N, Kohsaka S, Kadota K, Saito Y, Tsutsui H, Komuro I, Ikari Y, Ogawa H, Nakamura M. Primary Percutaneous Coronary Intervention in Elderly Patients With Acute Myocardial Infarction - An Analysis From a Japanese Nationwide Claim-Based Database -. Circulation Journal. 83, 1229-1238, 2019.
  18. Miyamoto K, Doi A, Hasegawa K, Morita Y, Mishima T, Suzuki I, Kaseno K, Nakajima K, Kataoka N, Kamakura T, Wada M, Yamagata K, Ishibashi K, Inoue YY, Nagase S, Noda T, Aiba T, Asakura M, Izumi C, Noguchi T, Tada H, Takagi M, Yasuda S, Kusano KF. Multicenter Study of the Validity of Additional Freeze Cycles for Cryoballoon Ablation in Patients With Paroxysmal Atrial Fibrillation The AD-Balloon Study. Circulation-Arrhythmia and Electrophysiology. 12, e006989, 2019.
  19. Shintani Y, Okada A, Morita Y, Hamatani Y, Amano M, Takahama H, Amaki M, Hasegawa T, Ohta-Ogo K, Kanzaki H, Ishibashi-Ueda H, Yasuda S, Shimazaki C, Yoshinaga T, Yazaki M, Sekijima Y, Izumi C. Monitoring treatment response to tafamidis by serial native T1 and extracellular volume in transthyretin amyloid cardiomyopathy. ESC Heart Failure. 6, 232-236, 2019.
  20. Kawarada O, Kume T, Zeno K, Nakamura S, Hozawa K, Akimitsu T, Asano H, Ando H, Yamamoto Y, Yamashita T, Shinozaki N, Odashiro K, Sato T, Yuba K, Sakanoue Y, Uzu T, Okada K, Fitzgerald PJ, Honda Y, Yasuda S. Cardiac function response to stenting in atherosclerotic renal artery disease with and without heart failure: results from the Carmel study. ESC Heart Failure. 6, 319-327, 2019.
  21. Nakayama T, Okada A, Hasegawa T, Morita Y, Kanzaki H, Yamashita K, Shimahara Y, Fujita T, Yasuda S, Kobayashi J. Feasibility of transcatheter prosthetic paravalvular leakage closure: a single-center, exploratory safety evaluation study of transcatheter closure of prosthetic paravalvular regurgitation in Japan (STOP PARA study). General Thoracic and Cardiovascular Surgery. 67, 493-500, 2019.
  22. Okamoto C, Okada A, Kanzaki H, Nishimura K, Hamatani Y, Amano M, Takahama H, Amaki M, Hasegawa T, Fujita T, Kobayashi J, Yasuda S, Izumi C. Prognostic impact of peak mitral inflow velocity in asymptomatic degenerative mitral regurgitation. Heart. 105, 609-615, 2019.
  23. Okura H, Saito Y, Soeda T, Nakao K, Ozaki Y, Kimura K, Ako J, Noguchi T, Yasuda S, Suwa S, Fujimoto K, Nakama Y, Morita T, Shimizu W, Hirohata A, Morita Y, Inoue T, Okamura A, Uematsu M, Hirata K, Tanabe K, Shibata Y, Owa M, Tsujita K, Nishimura K, Miyamoto Y, Ishihara M; J-MINUET investigators. Frequency and prognostic impact of intravascular imaging-guided urgent percutaneous coronary intervention in patients with acute myocardial infarction: results from J-MINUET. Heart and Vessels. 34, 564-571, 2019.
  24. Okuno T, Aoki J, Tanabe K, Nakao K, Ozaki Y, Kimura K, Ako J, Noguchi T, Yasuda S, Suwa S, Fujimoto K, Nakama Y, Morita T, Shimizu W, Saito Y, Hirohata A, Morita Y, Inoue T, Okamura A, Mano T, Hirata K, Shibata Y, Owa M, Tsujita K, Funayama H, Kokubu N, Kozuma K, Uemura S, Tobaru T, Saku K, Ohshima S, Nishimura K, Miyamoto Y, Ogawa H, Ishihara M. Association of onset-season with characteristics and long-term outcomes in acute myocardial infarction patients: results from the Japanese registry of acute myocardial infarction diagnosed by universal definition (J-MINUET) substudy. Heart and Vessels. 34, 1899-1908, 2019.
  25. Misumi K, Ogo T, Ueda J, Tsuji A, Fukui S, Konagai N, Asano R, Yasuda S. Development of Pulmonary Arterial Hypertension in a Patient Treated with Qing-Dai (Chinese Herbal Medicine). Internal Medicine. 58, 395-399, 2019.
  26. Nakamura K, Kanzaki H, Okada A, Amaki M, Takahama H, Hasegawa T, Sugano Y, Yasuda S, Anzai T. Independent Prognostic Value of Pulmonary Diffusing Capacity in Nonsmoking Patients with Chronic Heart Failure. International Heart Journal. 60, 366-373, 2019.
  27. Asano R, Ogo T, Ohta-Ogo K, Fukui S, Tsuji A, Ueda J, Konagai N, Fukuda T, Morita Y, Noguchi T, Kusano K, Anzai T, Ishibashi-Ueda H, Yasuda S. Prolonged QRS duration as a predictor of right ventricular dysfunction after balloon pulmonary angioplasty. International Journal of Cardiology. 280, 176-181, 2019.
  28. Ogata S, Nishimura K, Guzman-Castillo M, Sumita Y, Nakai M, Nakao YM, Nishi N, Noguchi T, Sekikawa A, Saito Y, Watanabe T, Kobayashi Y, Okamura T, Ogawa H, Yasuda S, Miyamoto Y, Capewell S, O'Flaherty M. Explaining the decline in coronary heart disease mortality rates in Japan: Contributions of changes in risk factors and evidence-based treatments between 1980 and 2012. International Journal of Cardiology. 291, 183-188, 2019.
  29. Hamatani Y, Amaki M, Yonezawa R, Yanagi Y, Jo Y, Amano M, Okada A, Takahama H, Hasegawa T, Kanzaki H, Yasuda S, Izumi C. Prevalence, determinants, and prognostic significance of exercise-induced pulmonary hypertension in patients with hypertrophic cardiomyopathy. International Journal of Cardiovascular Imaging. 35, 837-844, 2019.
  30. Shimizu W, Makimoto H, Yamagata K, Kamakura T, Wada M, Miyamoto K, Inoue-Yamada Y, Okamura H, Ishibashi K, Noda T, Nagase S, Miyazaki A, Sakaguchi H, Shiraishi I, Makiyama T, Ohno S, Itoh H, Watanabe H, Hayashi K, Yamagishi M, Morita H, Yoshinaga M, Aizawa Y, Kusano K, Miyamoto Y, Kamakura S, Yasuda S, Ogawa H, Tanaka T, Sumitomo N, Hagiwara N, Fukuda K, Ogawa S, Aizawa Y, Makita N, Ohe T, Horie M, Aiba T. Association of Genetic and Clinical Aspects of Congenital Long QT Syndrome With Life-Threatening Arrhythmias in Japanese Patients. JAMA Cardiology. 4, 246-254, 2019.
  31. Hochman JS, Reynolds HR, Bangalore S, O'Brien SM, Alexander KP, Senior R, Boden WE, Stone GW, Goodman SG, Lopes RD, Lopez-Sendon J, White HD, Maggioni AP, Shaw LJ, Min JK, Picard MH, Berman DS, Chaitman BR, Mark DB, Spertus JA, Cyr DD, Bhargava B, Ruzyllo W, Wander GS, Chernyavskiy AM, Rosenberg YD, Maron DJ; ISCHEMIA Research Group. Baseline Characteristics and Risk Profiles of Participants in the ISCHEMIA Randomized Clinical Trial. JAMA Cardiology. 4, 273-286, 2019.
  32. Takahama H, Nishikimi T, Takashio S, Hayashi T, Nagai-Okatani C, Asada T, Fujiwara A, Nakagawa Y, Amano M, Hamatani Y, Okada A, Amaki M, Hasegawa T, Kanzaki H, Nishimura K, Yasuda S, Kangawa K, Anzai T, Minamino N, Izumi C. Change in the NT-proBNP/Mature BNP Molar Ratio Precedes Worsening Renal Function in Patients With Acute Heart Failure: A Novel Predictor Candidate for Cardiorenal Syndrome. Journal of the American Heart Association. 8, e011468, 2019.
  33. Kanaoka K, Okayama S, Nakai M, Sumita Y, Onoue K, Soeda T, Nishimura K, Kawakami R, Okura H, Miyamoto Y, Yasuda S, Tsutsui H, Komuro I, Ogawa H, Saito Y. Number of Cardiologists per Cardiovascular Beds and In-Hospital Mortality for Acute Heart Failure: A Nationwide Study in Japan. Journal of the American Heart Association. 8, e012282, 2019.
  34. Yoshimoto T, Inoue M, Yamagami H, Fujita K, Tanaka K, Ando D, Sonoda K, Kamogawa N, Koga M, Ihara M, Toyoda K. Use of Diffusion-Weighted Imaging-Alberta Stroke Program Early Computed Tomography Score (DWI-ASPECTS) and Ischemic Core Volume to Determine the Malignant Profile in Acute Stroke. Journal of the American Heart Association. 8, e012558, 2019.
  35. Natsuaki M, Morimoto T, Watanabe H, Nakagawa Y, Furukawa Y, Kadota K, Akasaka T, Hanaoka KI, Kozuma K, Tanabe K, Morino Y, Muramatsu T, Kimura T; CREDO‐Kyoto PCI/CABG registry cohort‐2, RESET and NEXT trial investigators. Ischemic and Bleeding Risk After Percutaneous Coronary Intervention in Patients With Prior Ischemic and Hemorrhagic Stroke. Journal of the American Heart Association. 8, e013356, 2019.
  36. Yasuda S, Kaikita K, Akao M, Ako J, Matoba T, Nakamura M, Miyauchi K, Hagiwara N, Kimura K, Hirayama A, Matsui K, Ogawa H. Antithrombotic Therapy for Atrial Fibrillation with Stable Coronary Disease. New England Journal of Medicine. 381, 1103-1113, 2019.
  37. Nakashima T, Noguchi T, Tahara Y, Nishimura K, Yasuda S, Onozuka D, Iwami T, Yonemoto N, Nagao K, Nonogi H, Ikeda T, Sato N, Tsutsui H; Japanese Circulation Society with Resuscitation Science Study Group. Public-access defibrillation and neurological outcomes in patients with out-of-hospital cardiac arrest in Japan: a population-based cohort study. Lancet. Epub, 2019.
  38. Mihara G, Noguchi T, Nishii Y, Hayashi Y, Kawauchi S, Miura M. Rhodium-Catalyzed Annulative Coupling of Isothiazoles with Alkynes through N-S Bond Cleavage. Organic Letters. Epub, 2019.
  39. Sekiguchi N, Noguchi T, Fukushima T, Kobayashi T, Ozawa T, Sato Y, Takeda T, Yoshida K, Koizumi T. Posterior mediastinal ganglioneuroblastoma in an adolescent: A case report and review. Thorac Cancer. Epub, 2019.
  40. Ishii M, Kaikita K, Sakamoto K, Seki T, Kawakami K, Nakai M, Sumita Y, Nishimura K, Miyamoto Y, Noguchi T, Yasuda S, Tsutsui H, Komuro I, Saito Y, Ogawa H, Tsujita K; JROAD Investigators. Characteristics and in-hospital mortality of patients with myocardial infarction in the absence of obstructive coronary artery disease in super-aging society. International Journal of Cardiology. Epub, 2019.
  41. Shintani Y, Takahama H, Hamatani Y, Nishimura K, Kanzaki H, Kusano K, Noguchi T, Toyoda K, Yasuda S, Izumi C. Ischemic stroke risk during post-discharge phases of heart failure: association of left ventricular concentric geometry. Heart and Vessels. Epub, 2019.
  42. Iwai T, Kataoka Y, Otsuka F, Asaumi Y, Nicholls SJ, Noguchi T, Yasuda S. Chronic kidney disease and coronary atherosclerosis: evidences from intravascular imaging. Expert Review of Cardiovascular Therapy. 17, 707-716, 2019.
  43. Yasuda S, Honda S, Takegami M, Nishihira K, Kojima S, Asaumi Y, Suzuki M, Kosuge M, Takahashi J, Sakata Y, Takayama M, Sumiyoshi T, Ogawa H, Kimura K; JAMIR Investigators. Contemporary Antiplatelet Therapy and Clinical Outcomes of Japanese Patients With Acute Myocardial Infarction - Results From the Prospective Japan Acute Myocardial Infarction Registry (JAMIR) -. Circulation Journal. 83, 1633-1643, 2019.
  44. Kitahara S, Kataoka Y, Otsuka F, Hosoda H, Asaumi Y, Noguchi T, Yasuda S. Plaque erosion or coronary artery embolism? Findings from clinical presentation, optical coherence tomographic and histopathological analysis in a case with acute coronary syndrome. International Journal of Cardiovascular Imaging. 35, 1791-1792, 2019.
  45. Yumoto T, Naito H, Yorifuji T, Tahara Y, Yonemoto N, Nonogi H, Nagao K, Ikeda T, Sato N, Tsutsui H. Geographical Differences and the National Meeting Effect in Patients with Out-of-Hospital Cardiac Arrests: A JCS-ReSS Study Report. International Journal of Environmental Research and Public Health. 16, 5130, 2019.
  46. Jinno K, Hifumi T, Okazaki T, Kuroda Y, Tahara Y, Yonemoto N, Nonogi H, Nagao K, Ikeda T, Sato N, Tsutsui H; Japanese Circulation Society Resuscitation Science Study (JCS-ReSS) Group. Association Between Prehospital Supraglottic Airway Compared With Bag-Mask Ventilation and Glasgow-Pittsburgh Cerebral Performance Category 1 in Patients With Out-of-Hospital Cardiac Arrest. Circulation Journal. 83, 2479-2486, 2019.
  47. Sugane H, Kataoka Y, Otsuka F, Yasuda S. Cholesterol-crystalized coronary atheroma as a potential precursor lesion causing acute coronary syndrome: a case report. European Heart Journal-Case Reports. 3, ytz128, 2019.
  48. Hosoda H, Kataoka Y, Otsuka F, Yasuda S. Severely calcified lipidic atheroma on intravascular ultrasound and near-infrared spectroscopy imaging: its association with slow-flow phenomenon during percutaneous coronary intervention. European Heart Journal-Case Reports. 3, ytz078, 2019.
  49. Kato Y, Amaki M, Kanzaki H, Kataoka Y, Okada A, Miyamoto K, Hamatani Y, Amano M, Takahama H, Hasegawa T, Matsumoto Y, Fujita T, Kobayashi J, Ishibashi-Ueda H, Yasuda S, Izumi C. MitraClip Therapy for Healed Infective Endocarditis - How Long Should We Wait After Active Infection? -. Circulation Journal. Epub, 2019.
  50. Nakashima T, Noguchi T, Tahara Y, Nishimura K, Ogata S, Yasuda S, Onozuka D, Morimura N, Nagao K, Gaieski DF, Asai Y, Yokota H, Nara S, Hase M, Atsumi T, Sakamoto T; SAVE-J Group. Patients With Refractory Out-of-Cardiac Arrest and Sustained Ventricular Fibrillation as Candidates for Extracorporeal Cardiopulmonary Resuscitation - Prospective Multi-Center Observational Study -. Circulation Journal. 83, 1011-1018, 2019.
  51. Yagyu T, Ida K, Noguchi T, Yasuda S. Multiple Arterial Dissections in a Patient With Vascular Ehlers-Danlos Syndrome Caused by a Frameshift Mutation in COL3A1. Circulation Journal. 83, 2324, 2019.
  52. Munnur RK, Andrews J, Kataoka Y, Nerlekar N, Psaltis PJ, Nicholls SJ, Malaiapan Y, Cameron JD, Meredith IT, Seneviratne S, Wong DTL. Quantitative and Qualitative Coronary Plaque Assessment Using Computed Tomography Coronary Angiography: A Comparison With Intravascular Ultrasound. Heart, Lung and Circulation. Epub, 2019.
  53. Kiran RM, Andrews J, Kataoka Y, Psaltis PJ, Nicholls SJ, Malaiapan Y, Seneviratne S, Cameron JD, Wong DTL. Serial Coronary Plaque Assessment Using Computed Tomography Coronary Angiography: A Comparison With Intravascular Ultrasound. Circulation: Cardiovascular Imaging. 12, e008404, 2019.
  54. Shishikura D, Kataoka Y, Honda S, Takata K, Kim SW, Andrews J, Psaltis PJ, Sweeney M, Kulikowski E, Johansson J, Wong NCW, Nicholls SJ. The Effect of Bromodomain and Extra-Terminal Inhibitor Apabetalone on Attenuated Coronary Atherosclerotic Plaque: Insights from the ASSURE Trial. American Journal of Cardiovascular Drugs. 19, 49-57, 2019.
  55. Nishihira K, Yamashita A, Kataoka Y, Shibata Y, Asada Y. Visualization of Oxidized Low-density Lipoprotein at Lipid-rich Plaque in a ST-segment Elevation Myocardial Infarction Case with Heterozygous Familial Hypercholesterolemia: Insights from Near-infrared Spectroscopy and Histopathological Analysis. European Heart Journal-Cardiovascular Imaging. 20, 1316, 2019.
  56. Miyoshi T, Oku H, Asahara S, Okamoto A, Kokame K, Nakai M, Nishimura K, Otsuka F, Higashiyama A, Yoshimatsu J, Miyata T. Effects of low-dose combined oral contraceptives and protein S K196E mutation on anticoagulation factors: a prospective observational study. International Journal of Hematology. 109, 641-649, 2019.
  57. Kimura K, Kimura T, Ishihara M, Nakagawa Y, Nakao K, Miyauchi K, Sakamoto T, Tsujita K, Hagiwara N, Miyazaki S, Ako J, Arai H, Ishii H, Origuchi H, Shimizu W, Takemura H, Tahara Y, Morino Y, Iino K, Itoh T, Iwanaga Y, Uchida K, Endo H, Kongoji K, Sakamoto K, Shiomi H, Shimohama T, Suzuki A, Takahashi J, Takeuchi I, Tanaka A, Tamura T, Nakashima T, Noguchi T, Fukamachi D, Mizuno T, Yamaguchi J, Yodogawa K, Kosuge M, Kohsaka S, Yoshino H, Yasuda S, Shimokawa H, Hirayama A, Akasaka T, Haze K, Ogawa H, Tsutsui H, Yamazaki T; Japanese Circulation Society Joint Working Group. JCS 2018 Guideline on Diagnosis and Treatment of Acute Coronary Syndrome. Circulation Journal. 83, 1085-1196, 2019.
  58. Nishimoto Y, Fukuhara R, Otsuka F, Toma M, Miyamoto T, Sato Y. A superficial femoral artery calcification: insights from a multi-imaging modality assessment with computed tomography, electronic high-resolution angioscopy, and optical frequency domain imaging. Cardiovascular Intervention and Therapeutics. Epub, 2019.
  59. Hayashi H, Tsuji A, Asano R, Konagai N, Ueda J, Fukui S, Ogo T, Miyata S, Yasuda S. Successful multi-step catheter intervention for thrombotic inferior vena cava filter retrieval. Journal of Cardiology Cases. 20, 142-146, 2019.
  60. Yasuda S, Ogawa H; AFIRE Investigators. Antithrombotic Therapy for Atrial Fibrillation with Stable Coronary Disease. Reply. New England Journal of Medicine. 381, 2481, 2019.
  61. Yoneyama K, Kanaoka K, Okayama S, Nishimura K, Nakai M, Matsushita K, Miyamoto Y, Kida K, Ishibashi Y, Izumo M, Watanabe M, Soeda T, Okura H, Harada T, Yasuda S, Murohara T, Ogawa H, Saito Y, Akashi YJ. Association between the number of board-certified cardiologists and the risk of in-hospital mortality: a nationwide study involving the Japanese registry of all cardiac and vascular diseases. BMJ Open. 9, e024657, 2019.
  62. Hamatani Y, Shiraishi I, Nishii T, Okada A, Amaki M, Yamasahita K, Matsumoto Y, Kanzaki H, Fukuda T, Fujita T, Yasuda S, Kobayashi J, Izumi C. Multimodality imaging and three-dimensional printed model in patients with left ventricular outflow tract obstruction. ESC Heart Failure. Epub, 2019.
  63. Hasegawa T, Asakura M, Asanuma H, Amaki M, Takahama H, Sugano Y, Kanzaki H, Yasuda S, Anzai T, Izumi C, Kitakaze M. Difference in the prevalence of subclinical left ventricular impairment among left ventricular geometric pattern in a community-based population. Journal of Cardiology. Epub, 2019.
  64. Takada Y, Hamatani Y, Kawano Y, Anchi Y, Nakai M, Izumi C, Yasuda S, Ogawa H, Sugano Y, Anzai T, Shibata T, Suzuki A, Nishikawa M, Ito H, Kato M, Shiga T, Fukumoto Y. Development and validation of support tools for advance care planning in patients with chronic heart failure. International Journal of Palliative Nursing. 25, 494-502, 2019.
  65. Yanagi Y, Amaki M, Kato Y, Kanzaki H, Kusano K, Yasuda S, Izumi C. A case of right ventricular thrombus formation in Uhl's anomaly: usefulness of 3D transthoracic echocardiography for treatment follow-up. Journal of Medical Ultrasonics. Epub, 2019.
  66. Pocock SJ, Brieger D, Gregson J, Chen JY, Cohen MG, Goodman SG, Granger CB, Grieve R, Nicolau JC, Simon T, Westermann D, Yasuda S, Hedman K, Rennie KL, Sundell KA; TIGRIS Study Investigators. Predicting risk of cardiovascular events 1 to 3 years post-myocardial infarction using a global registry. Clinical Cardiology. 43, 24-32, 2019.
  67. Tadaki S, Sakata Y, Miura Y, Nochioka K, Miura M, Miyata S, Asakura M, Shimada K, Yamamoto T, Fukumoto Y, Kadokami T, Yasuda S, Miura T, Ando SI, Yano M, Kitakaze M, Daida H, Shimokawa H. Factors limiting habitual exercise in patients with chronic heart failure: a multicenter prospective cohort study. Heart and Vessels. Epub, 2019.
  68. Ueda N, Kamakura T, Noda T, Nakajima K, Kataoka N, Wada M, Yamagata K, Ishibashi K, Inoue Y, Miyamoto K, Nagase S, Aiba T, Izumi C, Noguchi T, Yasuda S, Kusano K. Efficacy and safety of new-generation atrial antitachycardia pacing for atrial tachyarrhythmias in patients implanted with cardiac resynchronization therapy devices. Journal of Cardiology. Epub, 2019.
  69. Ueda N, Noda T, Ishibashi K, Nakajima K, Kataoka N, Kamakura T, Wada M, Yamagata K, Inoue Y, Miyamoto K, Nagase S, Aiba T, Kanzaki H, Izumi C, Noguchi T, Yasuda S, Kusano K. Efficacy of a Device-Based Continuous Optimization Algorithm for Patients With Cardiac Resynchronization Therapy. Circulation Journal. 84, 18-25, 2019.
  70. Mizuno A, Niwa K, Ochiai R, Shiraishi I, Sumita Y, Daida H, Fukuda T, Miyamoto Y, Nishimura K, Ogawa H, Yasuda S. Impact of facilities accredited by both adult and pediatric cardiology societies on the outcome of patients with adult congenital heart disease. Journal of Cardiology. Epub, 2019.
  71. Takashio S, Takahama H, Nishikimi T, Hayashi T, Nagai-Okatani C, Matsuo A, Nakagawa Y, Amano M, Hamatani Y, Okada A, Amaki M, Hasegawa T, Kanzaki H, Yasuda S, Kangawa K, Anzai T, Minamino N, Izumi C. Superiority of proatrial natriuretic peptide in the prognostic power in patients with acute decompensated heart failure on hospital admission: comparison with B-type natriuretic peptide and other natriuretic peptide forms. Open Heart. 6, e001072, 2019.
  72. Tochiya M, Makino H, Tamanaha T, Matsuo M, Hishida A, Koezuka R, Ohata Y, Tomita T, Son C, Miyamoto Y, Yasuda S, Hosoda K. Effect of tofogliflozin on cardiac and vascular endothelial function in patients with type 2 diabetes and heart diseases: A pilot study. Journal of Diabetes Investigation. Epub, 2019.
  73. Yamagata K, Ishibashi K, Nakajima K, Kataoka N, Kamakura T, Wada M, Inoue Y, Miyamoto K, Nagase S, Noda T, Aiba T, Yasuda S, Kusano K. Comparing the catheter delivery system and the stylet delivery system for ventricular lead placement in pacemaker implantation-The CATS delivery system randomized controlled trial. Journal of Arrhythmia. 35, 524-527, 2019.
  74. Marume K, Ishibashi K, Noda T, Ohta-Ogo K, Yasuda S, Kusano K. Short coupled Torsade de pointes with myocardial injury: A possible sequela of myocarditis. Journal of Cardiology Cases. 19, 62-65, 2019.
  75. Konagai N, Fukui S, Kitano M, Fujimoto K, Nishii T, Ogo T, Yasuda S. Very Large Patent Ductus Arteriosus With Severe Pulmonary Arterial Hypertension. Circulation Journal. 83, 2325, 2019.
  76. Yamashita K, Fukushima S, Shimahara Y, Okada A, Amaki M, Kanzaki H, Izumi C, Yasuda S, Kobayashi J, Fujita T. Early outcomes of transcatheter mitral valve replacement for degenerated bioprosthesis in Japanese (MITRAL VIV study): a four-case series. General Thoracic and Cardiovascular Surgery. Epub, 2019.
  77. Toyoda K, Uchiyama S, Yamaguchi T, Easton JD, Kimura K, Hoshino H, Sakai N, Okada Y, Tanaka K, Origasa H, Naritomi H, Houkin K, Yamaguchi K, Isobe M, Minematsu K; CSPS.com Trial Investigators. Dual antiplatelet therapy using cilostazol for secondary prevention in patients with high-risk ischaemic stroke in Japan: a multicentre, open-label, randomised controlled trial. Lancet Neurology. 18, 539-548, 2019.
  78. Yamashita K, Fukushima S, Shimahara Y, Hamatani Y, Kanzaki H, Fukuda T, Izumi C, Yasuda S, Kobayashi J, Fujita T. Early outcomes of transcatheter aortic valve implantation for degenerated aortic bioprostheses in Japanese patients: insights from the AORTIC VIV study. General Thoracic and Cardiovascular Surgery. 67, 1038-1047, 2019.
  79. Kawarada O, Nakai M, Nishimura K, Miwa H, Iwasaki Y, Kanno D, Nakama T, Yamamoto Y, Ogata N, Nakamura M, Yasuda S. Antithrombotic therapy after femoropopliteal artery stenting: 12-month results from Japan Postmarketing Surveillance. Heart Asia. 11, e011114, 2019.
  80. Nakasuka K, Ishibashi K, Kamijima A, Kamakura T, Wada M, Inoue Y, Miyamoto K, Okamura H, Nagase S, Noda T, Aiba T, Yasuda S, Ohte N, Kusano K. Very long-term prognosis in patients with right ventricular apical pacing for sick sinus syndrome. Heart. 105, 1493-1499, 2019.
  81. Mishima T, Miyamoto K, Morita Y, Kamakura T, Nakajima K, Yamagata K, Wada M, Ishibashi K, Inoue Y, Nagase S, Noda T, Aiba T, Izumi C, Noguchi T, Yasuda S, Kusano K. Feasibility of late gadolinium enhancement magnetic resonance imaging to detect ablation lesion gaps in patients undergoing cryoballoon ablation of paroxysmal atrial fibrillation. Journal of Arrhythmia. 35, 190-196, 2019.
  82. Nakagawa S, Aiba T, Nakajima K, Kataoka N, Kamakura T, Wada M, Ishibashi K, Yamagata K, Inoue Y, Miyamoto K, Nagase S, Noda T, Miyamoto Y, Yasuda S, Shimizu W, Kusano K. Earthquake-Induced Torsade de Pointes in Long-QT Syndrome. Circulation Journal. 83, 1968, 2019.
  83. Ozawa T, Kawakami S, Matsumoto M, Ishibashi-Ueda H, Nagai T, Noguchi T, Yasuda S. Infective Endocarditis Involving Mitral Annular Calcification Leading to Abscess Formation Rupture Into Pericardium. Circulation Journal. 83, 1415, 2019.
  84. Funabashi S, Kawarada O, Hirano T, Ayabe S, Yagyu T, Noguchi T, Yasuda S. Awareness of Scleroderma Peripheral Artery Disease Presenting With Critical Limb Ischemia in Elderly Patients. Circulation Journal. 83, 1081, 2019.
  85. Asano R, Fukui S, Nishii T, Konagai N, Hasegawa T, Kitano M, Ogo T, Yasuda S. Platypnea-Orthodeoxia Syndrome Due to Atrial Septal Defect and Combined Thoracic Deformities in a Young Woman. Circulation Journal. 83, 1080, 2019.
  86. Doi T, Kawarada O, Yagyu T, Noguchi T, Yasuda S. Iliac artery stent fracture associated with hip joint flexion. Cardiovascular Intervention and Therapeutics. 34, 180-181, 2019.
  87. Funabashi S, Kawarada O, Yagyu T, Noguchi T, Yasuda S. The PICKING technique for self-expanding nitinol stent expansion of an extremely calcified lesion in the femoropopliteal artery: the tail makes the difference. Cardiovascular Intervention and Therapeutics. 34, 74-75, 2019.
  88. 野口 暉夫. MRIでどう評価する？ 循環器ジャーナル. 67, 554-558, 2019.
  89. 平山 敦士, 野口 暉夫. triple therapy, double therapy 心房細動を合併したPCI症例の治療戦略に関する最新の知見. Hospitalist. 7, 577-581, 2019.
  90. 浅海 泰栄. 新規心原性ショックに対する経皮的循環補助装置. 日本臨床 別冊 循環器症候群（第3版）I. 73-76, 2019.
  91. 浅海 泰栄. 至適薬物療法. 循環器内科. 85, 497-502, 2019.
  92. 中島 啓裕, 田原 良雄. 心停止と心停止後症候群の治療における社会復帰を目指した多職種連携. 救急医学. 43, 129-133, 2019.
  93. 柳生 剛, 安田 聡. 高位大動脈閉塞. 日本臨床 別冊 循環器症候群（第3版）II. 329-333, 2019.
  94. 細田 勇人, 田原 良雄. 心原性ショックの薬物治療. 救急・集中治療. 31, 710-713, 2019.
  95. 細田 勇人, 田原 良雄. 心原性ショック（病態・診断）. 救急・集中治療. 31, 597-600, 2019.
  96. 中西 道郎. 急性心筋梗塞のリハビリテーション. Heart View. 23, 482-486, 2019.
  97. 真玉 英生, 安田 聡. 『慢性冠動脈疾患診断ガイドライン（2018年改訂版）』について 外部評価委員会の立場から. Progress in Medicine. 39, 595-600, 2019.
  98. 岩井 雄大, 安田 聡. 循環器の薬の使い分け 総論. レジデントノート. 21, 773-776, 2019.
  99. 安田 聡, 浅海 泰栄. 冠動脈疾患合併の際の注意点. 日本内科学会雑誌. 108, 242-246, 2019.
  100. 大塚 文之, 安田 聡. 心疾患の先制医療. 臨床検査. 63, 18-24, 2019.
  101. 大塚 文之. 冠動脈血栓症・塞栓症. 日本臨床 別冊 循環器症候群（第3版）II. 105-109, 2019.