循環器病統合情報センター
研究活動の概要

　循環器病の情報を統括的に収集し、研究、医療施策に活用する体制を整備することはナショナルセンターとしての責務である。循環器病情報統括センターは、日本循環器学会とJROAD、JROAD-DPCを行うとともに、脳卒中に関しても脳卒中協会がおこなっていた脳卒中データバンク事業を行なっている。2018年は循環器専門医数と急性心筋梗塞の入院死亡率の関係（Circ J. 2018 Oct 25;82(11):2845-2851.）を他施設との共同研究として報告した。

研究業績
  1. Hamatani Y, Nagai T, Shiraishi Y, Kohsaka S, Nakai M, Nishimura K, Kohno T, Nagatomo Y, Asaumi Y, Goda A, Mizuno A, Yasuda S, Ogawa H, Yoshikawa T, Anzai T. Long-Term Prognostic Significance of Plasma B-Type Natriuretic Peptide Level in Patients With Acute Heart Failure With Reduced, Mid-Range, and Preserved Ejection Fractions. American Journal of Cardiology. 121, 731-738, 2018.
  2. Nakamura Y, Asaumi Y, Miyagi T, Nakai M, Nishimura K, Sugane H, Matama H, Kataoka Y, Miyamoto Y, Takeishi Y, Noguchi T, Yasuda S. Comparison of Long-Term Mortality in Patients With Previous Coronary Artery Bypass Grafting Who Underwent Percutaneous Coronary Intervention With Versus Without Optimal Medical Therapy. American Journal of Cardiology. 122, 206-212, 2018.
  3. Yoshitani K, Masui K, Kawaguchi M, Kawamata M, Kakinohana M, Kato S, Hasuwa K, Yamakage M, Yoshikawa Y, Nishiwaki K, Aoyama T, Inagaki Y, Yamasaki K, Matsumoto M, Ishida K, Yamashita A, Seo K, Kakumoto S, Hayashi H, Tanaka Y, Tanaka S, Ishida T, Uchino H, Kakinuma T, Yamada Y, Mori Y, Izumi S, Nishimura K, Nakai M, Ohnishi Y. Clinical Utility of Intraoperative Motor-Evoked Potential Monitoring to Prevent Postoperative Spinal Cord Injury in Thoracic and Thoracoabdominal Aneurysm Repair: An Audit of the Japanese Association of Spinal Cord Protection in Aortic Surgery Database. Anesthesia and Analgesia. 126, 763-768, 2018.
  4. Nakamura M, Fukukawa T, Kitagawa K, Nagai Y, Hosomi N, Minematsu K, Uchiyama S, Matsumoto M, Miyamoto Y. Ten-year standardization of lipids and high-sensitivity C-reactive protein in a randomized controlled trial to assess the effects of statins on secondary stroke prevention: Japan Statin Treatment Against Recurrent Stroke. Annals of Clinical Biochemistry. 55, 128-135, 2018.
  5. Choi YH, Kosaka T, Ojima M, Sekine S, Kokubo Y, Watanabe M, Miyamoto Y, Ono T, Amano A. Relationship between the burden of major periodontal bacteria and serum lipid profile in a cross-sectional Japanese study. BMC Oral Health. 18, 77, 2018.
  6. Miyoshi T, Hosoda H, Umekawa T, Asada T, Fujiwara A, Kurosaki K, Shiraishi I, Nakai M, Nishimura K, Miyazato M, Kangawa K, Ikeda T, Yoshimatsu J, Minamino N. Amniotic Fluid Natriuretic Peptide Levels in Fetuses With Congenital Heart Defects or Arrhythmias. Circulation Journal. 82, 2619-2626, 2018.
  7. Kanaoka K, Okayama S, Yoneyama K, Nakai M, Nishimura K, Kawata H, Horii M, Kawakami R, Okura H, Miyamoto Y, Akashi Y, Saito Y. Number of Board-Certified Cardiologists and Acute Myocardial Infarction-Related Mortality in Japan - JROAD and JROAD-DPC Registry Analysis -. Circulation Journal. 82, 2845-2851, 2018.
  8. Marume K, Noguchi T, Tateishi E, Morita Y, Kamakura T, Ishibashi K, Noda T, Miura H, Nishimura K, Nakai M, Yamada N, Tsujita K, Anzai T, Kusano K, Ogawa H, Yasuda S. Mortality and Sudden Cardiac Death Risk Stratification Using the Noninvasive Combination of Wide QRS Duration and Late Gadolinium Enhancement in Idiopathic Dilated Cardiomyopathy. Circulation: Arrhythmia and Electrophysiology. 11, e006233, 2018.
  9. Tatsumi Y, Morimoto A, Asayama K, Sonoda N, Miyamatsu N, Ohno Y, Miyamoto Y, Izawa S, Ohkubo T. Association between alcohol consumption and incidence of impaired insulin secretion and insulin resistance in Japanese: The Saku study. Diabetes Research and Clinical Practice. 135, 43786, 2018.
  10. Matsumoto M, Asaumi Y, Nakamura Y, Nakatani T, Nagai T, Kanaya T, Kawakami S, Honda S, Kataoka Y, Nakajima S, Seguchi O, Yanase M, Nishimura K, Miyamoto Y, Kusano K, Anzai T, Noguchi T, Fujita T, Kobayashi J, Ishibashi-Ueda H, Shimokawa H, Yasuda S. Clinical determinants of successful weaning from extracorporeal membrane oxygenation in patients with fulminant myocarditis. ESC Heart Failure. 5, 675-684, 2018.
  11. Inoue YY, Aiba T, Kawata H, Sakaguchi T, Mitsuma W, Morita H, Noda T, Takaki H, Toyohara K, Kanaya Y, Itoi T, Mitsuhashi T, Sumitomo N, Cho Y, Yasuda S, Kamakura S, Kusano K, Miyamoto Y, Horie M, Shimizu W. Different responses to exercise between Andersen-Tawil syndrome and catecholaminergic polymorphic ventricular tachycardia. Europace. 20, 1675-1682, 2018.
  12. Maniwa N, Fujino M, Nakai M, Nishimura K, Miyamoto Y, Kataoka Y, Asaumi Y, Tahara Y, Nakanishi M, Anzai T, Kusano K, Akasaka T, Goto Y, Noguchi T, Yasuda S. Anticoagulation combined with antiplatelet therapy in patients with left ventricular thrombus after first acute myocardial infarction. European Heart Journal. 39, 201-208, 2018.
  13. Nakao YM, Miyamoto Y, Higashi M, Noguchi T, Ohishi M, Kubota I, Tsutsui H, Kawasaki T, Furukawa Y, Yoshimura M, Morita H, Nishimura K, Kada A, Goto Y, Okamura T, Tei C, Tomoike H, Naito H, Yasuda S. Sex differences in impact of coronary artery calcification to predict coronary artery disease. Heart. 104, 1118-1124, 2018.
  14. Hashimoto T, Ako J, Nakao K, Ozaki Y, Kimura K, Noguchi T, Yasuda S, Suwa S, Fujimoto K, Nakama Y, Morita T, Shimizu W, Saito Y, Hirohata A, Morita Y, Inoue T, Okamura A, Uematsu M, Hirata K, Tanabe K, Shibata Y, Owa M, Tsujita K, Funayama H, Kokubu N, Kozuma K, Uemura S, Toubaru T, Saku K, Ohshima S, Nakai M, Nishimura K, Miyamoto Y, Ogawa H, Ishihara M. A lower eicosapentaenoic acid/arachidonic acid ratio is associated with in-hospital fatal arrhythmic events in patients with acute myocardial infarction: a J-MINUET substudy. Heart and Vessels. 33, 481-488, 2018.
  15. Kubota Y, Higashiyama A, Sugiyama D, Nishida Y, Kubo S, Hirata T, Kadota A, Miyamatsu N, Wakabayashi I, Miyamoto Y, Okamura T. Association between impairment of salty taste recognition and masked hypertension based on home blood pressure in Japanese residents: the KOBE study. Hypertension Research. 41, 756-762, 2018.
  16. Horiuchi Y, Aoki J, Tanabe K, Nakao K, Ozaki Y, Kimura K, Ako J, Yasuda S, Noguchi T, Suwa S, Fujimoto K, Nakama Y, Morita T, Shimizu W, Saito Y, Hirohata A, Morita Y, Inoue T, Okamura A, Uematsu M, Hirata K, Shibata Y, Nakai M, Nishimura K, Miyamoto Y, Ishihara M. A High Level of Blood Urea Nitrogen Is a Significant Predictor for In-hospital Mortality in Patients with Acute Myocardial Infarction. International Heart Journal. 59, 263-271, 2018.
  17. Hashimoto T, Ako J, Nakao K, Ozaki Y, Kimura K, Noguchi T, Yasuda S, Suwa S, Fujimoto K, Nakama Y, Morita T, Shimizu W, Saito Y, Hirohata A, Morita Y, Inoue T, Okamura A, Uematsu M, Hirata K, Tanabe K, Shibata Y, Owa M, Tsujita K, Funayama H, Kokubu N, Kozuma K, Uemura S, Toubaru T, Saku K, Oshima S, Nakai M, Nishimura K, Miyamoto Y, Ogawa H, Ishihara M. Pre-Procedural Thrombolysis in Myocardial Infarction Flow in Patients with ST-Segment Elevation Myocardial Infarction A J-MINUET Substudy. International Heart Journal. 59, 920-925, 2018.
  18. Honda S, Nagai T, Nishimura K, Nakai M, Honda Y, Nakano H, Iwakami N, Sugano Y, Asaumi Y, Aiba T, Noguchi T, Kusano K, Yokoyama H, Ogawa H, Yasuda S, Anzai T; NaDEF investigators. Long-term prognostic significance of urinary sodium concentration in patients with acute heart failure. International Journal of Cardiology. 254, 189-194, 2018.
  19. Nakano H, Nagai T, Sundaram V, Nakai M, Nishimura K, Honda Y, Honda S, Iwakami N, Sugano Y, Asaumi Y, Aiba T, Noguchi T, Kusano K, Yokoyama H, Ogawa H, Yasuda S, Chikamori T, Anzai T. Impact of iron deficiency on long-term clinical outcomes of hospitalized patients with heart failure. International Journal of Cardiology. 261, 114-118, 2018.
  20. Kinoshita M, Yokote K, Arai H, Iida M, Ishigaki Y, Ishibashi S, Umemoto S, Egusa G, Ohmura H, Okamura T, Kihara S, Koba S, Saito I, Shoji T, Daida H, Tsukamoto K, Deguchi J, Dohi S, Dobashi K, Hamaguchi H, Hara M, Hiro T, Biro S, Fujioka Y, Maruyama C, Miyamoto Y, Murakami Y, Yokode M, Yoshida H, Rakugi H, Wakatsuki A, Yamashita S. Japan Atherosclerosis Society (JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Diseases 2017. Journal of Atherosclerosis and Thrombosis. 25, 846-984, 2018.
  21. Kawakami H, Aiba T, Ishibashi K, Nakajima I, Wada M, Kamakura T, Inoue Y, Miyamoto K, Okamura H, Nagase S, Noda T, Kokubo Y, Miyamoto Y, Yasuda S, Kamakura S, Kusano K. Change in QRS morphology as a marker of spontaneous elimination in verapamil-sensitive idiopathic left ventricular tachycardia. Journal of Cardiovascular Electrophysiology. 29, 446-455, 2018.
  22. Sakurai M, Nakagawa H, Kadota A, Yoshita K, Nakamura Y, Okuda N, Nishi N, Miyamoto Y, Arima H, Ohkubo T, Okamura T, Ueshima H, Okayama A, Miura K. Macronutrient Intake and Socioeconomic Status: NIPPON DATA2010. Journal of Epidemiology. 28, S17-S22, 2018.
  23. Asayama K, Ohkubo T, Satoh A, Tanaka S, Higashiyama A, Murakami Y, Yamada M, Saitoh S, Okayama A, Miura K, Ueshima H, Miyamoto Y, Okamura T. Cardiovascular risk and blood pressure lowering treatment among elderly individuals: Evidence for Cardiovascular Prevention from Observational Cohorts in Japan. Journal of Hypertension. 36, 410-418, 2018.
  24. Hino T, Yokota C, Nishimura K, Nakai M, Kato S, Kuwabara K, Takekawa H, Arimizu T, Tomari S, Wada S, Ohnish H, Toyoda K, Okamura T, Minematsu K. Spreading Awareness of Stroke through School-Based Education: A Pooled Analysis of Three Community-Based Studies. Journal of Stroke & Cerebrovascular Diseases. 27, 1810-1814, 2018.
  25. Kokubo Y, Watanabe M, Higashiyama A, Nakao YM, Nakamura F, Miyamoto Y. Impact of Intima-Media Thickness Progression in the Common Carotid Arteries on the Risk of Incident Cardiovascular Disease in the Suita Study. Journal of the American Heart Association. 7, e007720, 2018.
  26. Kurogi R, Nishimura K, Nakai M, Kada A, Kamitani S, Nakagawara J, Toyoda K, Ogasawara K, Ono J, Shiokawa Y, Aruga T, Miyachi S, Nagata I, Matsuda S, Yoshimura S, Okuchi K, Suzuki A, Nakamura F, Onozuka D, Ido K, Kurogi A, Mukae N, Nishimura A, Arimura K, Kitazono T, Hagihara A, Iihara K. Comparing intracerebral hemorrhages associated with direct oral anticoagulants or warfarin. Neurology. 90, e1143-e1149, 2018.
  27. Nakao YM, Miyamoto Y, Ueshima K, Nakao K, Nakai M, Nishimura K, Yasuno S, Hosoda K, Ogawa Y, Itoh H, Ogawa H, Kangawa K, Nakao K. Effectiveness of nationwide screening and lifestyle intervention for abdominal obesity and cardiometabolic risks in Japan: The metabolic syndrome and comprehensive lifestyle intervention study on nationwide database in Japan (MetS ACTION-J study). PLOS ONE. 13, e0190862, 2018.
  28. Hamatani Y, Nagai T, Nakai M, Nishimura K, Honda Y, Nakano H, Honda S, Iwakami N, Sugano Y, Asaumi Y, Aiba T, Noguchi T, Kusano K, Toyoda K, Yasuda S, Yokoyama H, Ogawa H, Anzai T. Elevated Plasma D-Dimer Level Is Associated With Short-Term Risk of Ischemic Stroke in Patients With Acute Heart Failure. Stroke. 49, 1737-1740, 2018.
  29. Miyoshi T, Umekawa T, Hosoda H, Asada T, Fujiwara A, Kurosaki KI, Shiraishi I, Nakai M, Nishimura K, Miyazato M, Kangawa K, Ikeda T, Yoshimatsu J, Minamino N. Plasma natriuretic peptide levels in fetuses with congenital heart defect and/or arrhythmia. Ultrasound in Obstetrics & Gynecology. 52, 609-616, 2018.
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  34. 宮本 恵宏. 女性医療における循環器疾患～心血管病予防に向けた女性のオーダーメイド医療～ 吹田研究からみた女性の循環器疾患. 日本女性医学学会雑誌. 25, 251-253, 2018.
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