| 主要論文・著書 |
論文
- Sawamura, T., Kume, N., Aoyama, T., Moriwaki, H., Hoshikawa, H., Aiba, Y., Tanaka, T., Miwa, S., Katsura, Y., Kita, T. and Masaki, T.: An endothelial receptor for oxidized low-density lipoprotein. Nature, 386:73-77, 1997.
- Hosokawa, H., Sawamura, T., Kobayashi, S., Ninomiya, H., Miwa, S. and Masaki, T.: Cloning and characterization of a brain-specific cationic amino acid transporter. J Biol Chem, 272:8717-8722, 1997.
- Oka, K., Sawamura, T., Kikuta, K., Itokawa, S., Kume, N., Kita, T. and Masaki, T.: Lectin-like oxidized low-density lipoprotein receptor 1 mediates phagocytosis of aged/apoptotic cells in endothelial cells. Proc Natl Acad Sci U S A, 95:9535-9540, 1998.
- Kikuta, K., Sawamura, T., Miwa, S., Hashimoto, N. and Masaki, T.: High-affinity arginine transport of bovine aortic endothelial cells is impaired by lysophosphatidylcholine. Circ Res, 83:1088-1096, 1998.
- Kakutani, M., Masaki, T. and Sawamura, T.: A platelet-endothelium interaction mediated by lectin-like oxidized low-density lipoprotein receptor-1. Proc Natl Acad Sci U S A, 97:360-364, 2000.
- Delneste, Y., Magistrelli, G., Gauchat, J., Haeuw, J., Aubry, J., Nakamura, K., Kawakami-Honda, N., Goetsch, L., Sawamura, T., Bonnefoy, J. and Jeannin, P.: Involvement of LOX-1 in dendritic cell-mediated antigen cross-presentation. Immunity, 17:353, 2002.
- Honjo, M., Nakamura, K., Yamashiro, K., Kiryu, J., Tanihara, H., McEvoy, L.M., Honda, Y., Butcher, E.C., Masaki, T. and Sawamura, T.: Lectin-like oxidized LDL receptor-1 is a cell-adhesion molecule involved in endotoxin-induced inflammation. Proc Natl Acad Sci U S A, 100:1274-1279, 2003.
- Li, L., Roumeliotis, N., Sawamura, T. and Renier, G.: C-reactive protein enhances LOX-1 expression in human aortic endothelial cells. Relevance of LOX-1 to C-reactive protein-induced endothelial dysfunction. Circ Res, 95:877-883, 2004.
- Inoue, K., Arai, Y., Kurihara, H., Kita, T. and Sawamura, T.: Overexpression of lectin-like oxidized low-density lipoprotein receptor-1 induces intramyocardial vasculopathy in apolipoprotein E-null mice. Circ Res, 97:176-184, 2005.
- Hinagata, J., Kakutani, M., Fujii, T., Naruko, T., Inoue, N., Fujita, Y., Mehta, J.L., Ueda, M. and Sawamura, T.: Oxidized LDL receptor LOX-1 is involved in neointimal hyperplasia after balloon arterial injury in a rat model. Cardiovasc Res, 69:263-271, 2006.
- Mehta, J.L., Sanada, N., Hu, C.P., Chen, J., Dandapat, A., Sugawara, F., Satoh, H., Inoue, K., Kawase, Y., Jishage, K., Suzuki, H., Takeya, M., Schnackenberg, L., Beger, R., Hermonat, P.L., Thomas, M. and Sawamura, T.: Deletion of LOX-1 reduces atherogenesis in LDLR knockout mice fed high cholesterol diet.
- Yao, E.H., Fukuda, N., Ueno, T., Matsuda, H., Matsumoto, K., Nagase, H., Matsumoto, Y., Takasaka, A., Serie, K., Sugiyama, H. and Sawamura, T.: Novel gene silencer pyrrole-imidazole polyamide targeting lectin-like oxidized low-density lipoprotein receptor-1 attenuates restenosis of the artery after injury. Hypertension, 52:86-92, 2008.
- Ishigaki, Y., Katagiri, H., Gao, J., Yamada, T., Imai, J., Uno, K., Hasegawa, Y., Kaneko, K., Ogihara, T., Ishihara, H., Sato, Y., Takikawa, K., Nishimichi, N., Matsuda, H., Sawamura, T. and Oka, Y.: Impact of plasma oxidized low-density lipoprotein removal on atherosclerosis. Circulation, 118:75-83, 2008.
- Lu, J., Yang, J.H., Burns, A.R., Chen, H.H., Tang, D., Walterscheid, J.P., Suzuki, S., Yang, C.Y., Sawamura, T. and Chen, C.H.: Mediation of electronegative low-density lipoprotein signaling by LOX-1: a possible mechanism of endothelial apoptosis. Circ Res, 104:619-627, 2009.
- Ueno, T., Fukuda, N., Tsunemi, A., Yao, E.H., Matsuda, H., Tahira, K., Matsumoto, T., Matsumoto, K., Matsumoto, Y., Nagase, H., Sugiyama, H. and Sawamura, T.: A novel gene silencer, pyrrole-imidazole polyamide targeting human lectin-like oxidized low-density lipoprotein receptor-1 gene improves endothelial cell function. J Hypertens, 27:508-516, 2009.
- Fujita, Y., Kakino, A., Nishimichi, N., Yamaguchi, S., Sato, Y., Machida, S., Cominacini, L., Delneste, Y., Matsuda, H. and Sawamura, T.: Oxidized LDL receptor LOX-1 binds to C-reactive protein and mediates its vascular effects. Clin Chem, 55:285-294, 2009.
- Nakano, A., Inoue, N., Sato, Y., Nishimichi, N., Takikawa, K., Fujita, Y., Kakino, A., Otsui, K., Yamaguchi, S., Matsuda, H. and Sawamura, T.: LOX-1 mediates vascular lipid retention under hypertensive state. J Hypertens, 28:1273-1280, 2010.
|
